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Study of Stroke Volume Variation and Pleth Variability Index as Predictors of Fluid Responsiveness

Validation of Stroke Volume Variation and Pleth Variability Index as Predictors of Fluid Responsiveness in Patients Undergoing Robot Assisted Thyroidectomy

Status
UNKNOWN
Phases
Phase 4
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT02122367
Enrollment
48
Registered
2014-04-24
Start date
2014-04-30
Completion date
Unknown
Last updated
2014-04-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Fluid Responsiveness, Thyroidectomy

Brief summary

Appropriate indices to guide fluid therapy are essential for effective hemodynamic management during the perioperative period. Values derived from respiratory changes in arterial pressure waveform or plethysmographic waveform such as stroke volume variation and pleth variability index have been demonstrated to be able to predict fluid responsiveness in surgical or critically ill patients. Their ability to predict fluid responsiveness can be affected by factors that influence the arterial tone or the compliance of the respiratory system by position change. The aim of this prospective trial is to investigate the ability of stroke volume variation and pleth variability index to predict fluid responsiveness in the reverse trendelenberg position.

Interventions

OTHERHES 130/0.4 (VolulyteⓇ, Fresenius Kabi, Canada)

HES 130/0.4 (VolulyteⓇ, Fresenius Kabi, Canada) 6ml/kg of ideal body weight loading

Sponsors

Chung-Ang University Hosptial, Chung-Ang University College of Medicine
Lead SponsorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
20 Years to 70 Years
Healthy volunteers
No

Inclusion criteria

1. Age ≥ 20 2. elective robot assisted thyroidectomy

Exclusion criteria

1. arrhythmia 2. BMI\>30 3. valvular heart disease 4. pul hypertension 5. peripheral artery occlusive disease 6. lung disease 7. right heart failure

Design outcomes

Primary

MeasureTime frame
stroke volume variation5 minutes after volume replacement
pleth variability index5 minutes after volume replacement

Countries

South Korea

Contacts

Primary ContactSo-young Yang, clinical assistant professor
didth79@hanmail.net82-2-6299-3160
Backup ContactYong-hun Jung, professor
jyh623@cau.ac.kr82-2-6299-2579

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026