COPD, Lung Cancer
Conditions
Brief summary
Pulmonary rehabilitation might be benificial in advanced lung cancer patients with COPD who undergo cytotoxic chemotherapy. We will compare two groups, 8 week pulmonary rehabilitation group and usual care group.
Interventions
BEHAVIORALpulmonary rehabilitation
Sponsors
Seoul National University Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
20 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* pathologically proven lung cancer * chronic obstructive pulmonary disease * age \> 20 * ECOG 0-1 * cytotoxic chemotherapy
Exclusion criteria
* other history of cancer within 5 years * other major disease associated with heart, lung, neurology, mental and metabolic disorders * osteolytic bone metastatis to weight bearing site * uncontrolled infection
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| difference of VO2 max | 8 weeks | difference maximal oxygen consumption during exercise cardiopulmonary test between before and after intervention/control |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| difference of Saint George's Respiratory Questionannaire (SGRQ) score | 8 weeks | the difference of SGRQ score |
| difference of pulmonary function test | 8 weeks | the difference of FVC and FEV1 |
| difference of 6 min walk test | 8 weeks | the difference of 6 minute walk test |
| difference of depression test | 8 weeks | using Hospital Anxiety and Depression scale (HADS), measure the difference HADS between before and after intervention/control |
Countries
South Korea
Contacts
Primary ContactYoung Sik Park, Dr
Outcome results
None listed