Diagnostic Accuracy of Ultrasonography in Detecting Benign Radiolucent Lesions

Diagnostic Accuracy of Ultrasonography in Detecting Benign Radiolucent Lesions Compared to CBCT Imaging and Histological Examination

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02121236

Enrollment

Registered

2014-04-23

Start date

2014-04-30

Completion date

2015-03-31

Last updated

2015-03-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Benign Radiolucent Lesions

Keywords

CBCT, Ultrasonic diagnosis, Benign radiolucent lesions, Histopathology

Brief summary

This is an in vivo study which aims to evaluate the diagnostic accuracy of ultrasonography in detecting benign radiolucent lesion in the both jaws. The ultrasonography-based diagnosis of contents will be compared to those findings obtained from the histological examination (i.e. the gold standard). The second part of this study will examine the measuring accuracy by comparing ultrasonography-based 3D measurements with those obtained from CBCT images of the lesion assuming that CBCT 3D measurements are the gold standard.

Detailed description

Jaw is a common anatomical site for development of odontogenic and nonodontogenic lesions, and because of the wide variation of these lesions, the diagnosis is complex. Many techniques have been used to arrive at the final diagnosis such as conventional radiographs, computed tomography (CT), low dose cone beam CT, MRI.The use of ultrasonography has been shown to be important in evaluating the solid and cystic components of jaw lesions. Although ultrasound imaging technology is a safe and a minimally invasive procedure, and has been in use in medicine for many years, its use in dental medicine has been limited and mainly restricted to soft tissue applications. Studies evaluating the role of ultrasonography in the diagnosis of bone lesions of the jaw are limited.

Interventions

None listed

Study design

Observational model

CASE_ONLY

Time perspective

CROSS_SECTIONAL

Eligibility

Sex/Gender

ALL

Age

20 Years to 50 Years

Healthy volunteers

Inclusion criteria

* the presence of a radiolucent or mixed-appearance intraosseous lesion in the upper or lower jaw requiring surgical removal * no previous trauma to the maxillofacial region. * no previous surgical intervention in the same area of the lesion.

Exclusion criteria

* the presence of a completely radiopaque lesion indicating solid content. * patients with systemic conditions associated with bony pathology such as hyperparathyroidism, Paget disease, ﬁbrous dysplasia, multiple myeloma, etc...

Design outcomes

Primary

Measure	Time frame	Description
Lesion Contents	One time assessment once sample recruitment has completed. Ultrasonographic images will be taken before the surgical intervention of the lesion, whereas the histological examination will be performed after the surgical removal	Three possible categories for this variable: Solid, liquid, mixed.

Secondary

Measure	Time frame
3D measurements of the lesion	One time assessment once sample recruitment has completed.

Countries

Syria

Outcome results