Research of Resistance to Antiplatelet Agents and Development of Tailored Treatment Model for Patients With Coronary Artery Disease

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02121054

Enrollment

1527

Registered

2014-04-23

Start date

2013-10-19

Completion date

2020-10-29

Last updated

2023-03-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cardiovascular Diseases, Coronary Artery Disease

Keywords

Antiplatelet Agents, Drug Resistance

Brief summary

The purpose of this study is to evaluate the prognosis of patients with resistance to antiplatelet agent and develop tailored treatment model for patients with coronary artery disease.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

20 Years to No maximum

Healthy volunteers

Inclusion criteria

* Age \>20 * Patients with coronary artery disease * Patients with peripheral artery disease

Exclusion criteria

* Renal dysfunction * Hepatic dysfunction * Major surgery planned within 1 year * Malignant tumor * History of gastrointestinal bleeding * low or high platelet count

Design outcomes

Primary

Measure	Time frame	Description
Major adverse event	2 year	Major adverse event : overall mortality, cardiovascular mortality, target vessel revascularization

Secondary

Measure	Time frame	Description
Biomarker	2 year	homocysteine, Lp(a), fibrinogen, PAI-1, NTpro-BNP, hs-CRP, matrix metalloproteinase-9, soluble CD40L, IL-6, serum amyloid A, AGE

Countries

South Korea

Outcome results