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Pigtail Catheter: a Less Invasive Option for Pleural Drainage of Recurrent Hepatic Hydrothorax

Pigtail Catheter: a Less Invasive Option for Pleural Drainage of Recurrent Hepatic Hydrothorax

Status
UNKNOWN
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT02119169
Acronym
HH
Enrollment
30
Registered
2014-04-21
Start date
2014-03-31
Completion date
2022-12-31
Last updated
2017-12-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pleural Effusion

Brief summary

The effectiveness of pigtail catheter as a less invasive option for pleural drainage in patients with resistant hepatic hydrothorax.

Detailed description

Hepatic hydrothorax (HH) is defined as a transudative pleural effusion in patients with liver cirrhosis in the absence of cardiopulmonary disease. The estimated prevalence among patients with liver cirrhosis is approximately 5-6% (Baikati et al., 2014). HH is an infrequent but a well-known complication of portal hypertension. Trans-diaphragmatic passage of ascitic fluid from peritoneal to the pleural cavity through numerous diaphragmatic defects has been shown to be the predominant mechanism in the formation of HH (Kumar&Kumar, 2014). Patients with hepatic hydrothoraces often have few options (Goto et al., 2011). Diuretic-resistant HH could be managed with liver transplantation, transjugular intrahepatic portosystemic shunt (TIPS) or indwelling pleural catheters. However, tube thoracotomy and pleurodesis failed in most patients (Singh et al., 2013). Case reports and small case series have reported a high rate of complications associated with chest tube placement for hepatic hydrothorax. The most common reported complications were acute kidney injury, pneumothorax, and empyema. Death has been recorded in some cases. Chest tube insertion for hepatic hydrothorax carries significant morbidity and mortality, with questionable benefit (Orman&Lok, 2009). Pigtail catheter insertion is an effective and safe method of draining pleural fluid. Its use is safe and recommended for all cases of pleural effusion requiring chest drain except for empyema and other loculated effusions that yielded low success rate (Bediwy and Amer, 2012).

Interventions

pigtail catheter for pleural drainage

Sponsors

Tanta University
CollaboratorOTHER
Sherief Abd-Elsalam
Lead SponsorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to 70 Years
Healthy volunteers
No

Inclusion criteria

* Patients with cirrhotic liver and recurrent pleural effusion. * Pleural fluid should be transudate according to Light's criteria: * Pleural fluid-to-serum protein ratio less than 0.5 * Pleural fluid lactic dehydrogenase (LDH) less than 200 IU * Pleural fluid-to-serum LDH ratio and pleural fluid-to-high normal serum LDH ratio less than 0.6

Exclusion criteria

* Diagnosis of hepatocellular carcinoma or other neoplasm able to shorten life expectancy. * Congestive heart failure. * Recent (i.e. within the previous 2 weeks) episode of digestive hemorrhage. * Exudative pleural effusion. * Ascitic fluid or pleural fluid infection * Platelet count below 50,000 * Prothrombin activity below 50%

Design outcomes

Primary

MeasureTime frame
Change in chest radiographybaseline, daily after treatment within admission

Secondary

MeasureTime frame
Chest X-ray and any complications recordedweekly in first month and monthly for 3 months

Countries

Egypt

Contacts

Primary ContactSherief M Abd-Elsalam, doctor
Sherif_tropical@yahoo.com00201000040794

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 2, 2026