Decompression Sickness, Endothelial Dysfunction, Neutrophil Activation, Venous Gas Emboli
Conditions
Keywords
SCUBA diving, Exercise, Microparticles, Repetitive diving, Endothelial function
Brief summary
SCUBA diving frequently involves repetitive exposures over multiple days. The goal of this study was to see how exercise impacts microparticles (MPs), endothelial function, and venous gas emboli (VGE) over a series of dives. 16 divers in 2 groups each completed 6 dives. One group completed 3 control dives followed by 5 days rest then 3 dives preceded by exercise. The other group completed the opposite protocol. Flow-mediated dilation (FMD) data and blood for MP analysis was collected before and after each dive. VGE were monitored via transthoracic echocardiography 30, 60, and 90 min after surfacing. Exercise before diving consisted of 60 min running outdoors including 8x4 min intervals at 90% VO2max effort.
Interventions
OTHERAerobic running exercise
60 min of aerobic intervals completed prior to SCUBA diving
Sponsors
University of Maryland
University of Split
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
BASIC_SCIENCE
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
Yes
Inclusion criteria
* Certified SCUBA diver * Certified to dive by experienced Medical evaluator * Must be able to run continuously for 45 min
Exclusion criteria
* Prior diagnosis of decompression sickness
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change in circulating microparticle counts | 2 weeks | Change in circulating microparticle counts measured pre and post SCUBA diving following 6 dives spaced over 12 days |
Countries
Croatia, United States
Outcome results
None listed