Functional Gastrointestinal Disorders in Children
Conditions
Keywords
functional gastrointestinal disorders, FGID, children, FODMAP
Brief summary
This pilot study aims to establish whether a low FODMAP diet is safe in children with functional gastrointestinal disorders. The practicality of implementing this diet will be evaluated as well as symptom improvement and quality of life. A larger intervention trial, if deemed appropriate, will then follow to assess symptom efficacy in children.
Interventions
OTHERFODMAP's diet
The safety and efficacy of a low FODMAP diet will be evaluated in a convenience sample of children with functional gastrointestinal disorders, over a 6 week intervention period.
Sponsors
University of London
Dr Anne Payne
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
10 Years to 16 Years
Healthy volunteers
No
Inclusion criteria
* Patients aged 10-16 years * Informed consent and assent obtained * Patients with diagnosed FGID according to Rome III criteria: i.e. category H2b (irritable bowel syndrome) and H2d (childhood functional abdominal pain)
Exclusion criteria
* Patients with other gastrointestinal conditions (e.g. coeliac disease, inflammatory bowel disease) * Patients with food allergies * Patients with a weight for age below -2 Standard Deviations (SD) (below 0.4th centile) on the UK WHO growth charts. * Patients with known micronutrient deficiencies determined by blood levels prior to study * Patients without informed consent and assent obtained
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Energy and nutrient intake | Baseline, 6 weeks | Energy and nutrient intake will be assessed using a 4-day estimated food diary at baseline and 6-weeks after dietary intervention. Comparison will be made between baseline and 6-week data and with United Kingdom (UK) Reference Nutrient Intakes. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Practicality of the FODMAP diet; impact of diet on Functional Gastro-Intestinal .Disorders (FGID) symptoms and stools | Baseline, 6 weeks | Practicality of the FODMAP diet will be evaluated using a standardised structured questionnaire. The impact of a low FODMAP diet on FGID symptoms and stools will be assessed using a validated symptom questionnaire and the Bristol Stool Chart. The impact of a low FODMAP diet on quality of life will be assessed using the Pediatric Quality of Life Inventory (PedsQL) Gastrointestinal Symptoms Module. |
| Anthropometry: weight and mid-arm circumference | Baseline, 6 weeks | Anthropometric measurements will be taken at baseline and 6 weeks after dietary intervention. Comparison will be made between baseline and 6-week data for weight and mid upper arm circumference, as well as comparing both baseline and 6-week data to the UK-WHO growth standards. |
Countries
United Kingdom
Contacts
Primary ContactClaire de Koker, BSc (Hons)
Outcome results
None listed