Healthy
Conditions
Keywords
volunteers
Brief summary
Presently, the gold standard for testing diet acid intake is a urine collection done for many hours, usually 24 hours, which must be analyzed in a research lab for net acid excretion. So, getting information about diet acid intake is difficult. Many people have suggested doing a much simpler test, which is checking the pH of the urine when you wake up. But, no one has studied if this simpler method is a valid method for estimating the 24 hour net acid excretion. Diet acid load may be important in many diseases associated with aging, such as loss of bone and muscle, and the development of kidney disease.
Detailed description
the primary outcome variable is morning urine pH and 24 hour urine net acid excretion
Interventions
OTHERhigh or low acid diet
high or low acid diets
Sponsors
optimal wellness labs
University of California, San Francisco
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
DIAGNOSTIC
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
Yes
Inclusion criteria
* no medical or psychological problems * able to come to UCSF for study
Exclusion criteria
* pregnant or trying to become pregnant * Hg \< 10 * abnormal screening labs * anyone unable to follow study directions
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| high acid diet | 6 months | correlation between first morning urine pH and 24 hour net acid excretion |
| low acid diet | 6 months | correlation between first morning urine pH and 24 hour net acid excretion |
Countries
United States
Outcome results
None listed