PRimary Prevention Of Depression in Offspring of Depressed Parents

Conditions

Depression

Keywords

Depression, Prevention, Adolescent, Child, Randomised Controlled Trial, Risk, Cognitive behavioural therapy, Group-based therapy

Brief summary

The purpose of this randomised controlled trial is to see whether a group-based psychological intervention for families can reduce the inflated risk of depression in children and adolescents who have at least one parent who suffers from depression (or who has suffered from depressed in the child's lifetime).

Löchner J, Platt B, Starman-Wöhrle K, Takano K, Engelmann L, Voggt A, Loy F, Bley M, Winogradow D, Hämmerle S, Neumeier E, Wermuth I, Schmitt K, Oort F, Schulte-Körne G.

2023-06-215 citations

10.1186/s12888-023-04926-2

A randomised controlled trial of a family-group cognitive-behavioural (FGCB) preventive intervention for the children of parents with depression: short-term effects on symptoms and possible mechanisms.

Löchner J, Starman-Wöhrle K, Takano K, Engelmann L, Voggt A, Loy F, Bley M, Winogradow D, Hämmerle S, Neumeier E, Wermuth I, Schmitt K, Oort F, Schulte-Körne G, Platt B.

2021-10-015 citations

10.1186/s13034-021-00394-2

Qualitative evaluation of a preventive intervention for the offspring of parents with a history of depression.

Claus N, Marzano L, Loechner J, Starman K, Voggt A, Loy F, Wermuth I, Haemmerle S, Engelmann L, Bley M, Schulte-Koerne G, Platt B.

2019-09-186 citations

10.1186/s12888-019-2273-6

Study protocol for a randomised controlled trial of a cognitive-behavioural prevention programme for the children of parents with depression: the PRODO trial.

Platt B, Pietsch K, Krick K, Oort F, Schulte-Körne G.

2014-09-1813 citations

10.1186/s12888-014-0263-2

Interventions

BEHAVIORALPrevention programme

Based on a group- and family-based cognitive behavioural manual developed by Bruce Compas and colleagues in the USA, and adapted for a German sample. The programme is for parents and children and consists of 8 weekly sessions and 4 monthly booster sessions.

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

PREVENTION

Masking

SINGLE (Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

8 Years to 17 Years

Healthy volunteers

Yes

Inclusion criteria

* At least one parent who meets diagnostic criteria for a current (or past, during the child's lifetime) diagnosis of depression * The participating child is aged 8-17 * The participating child has an IQ of at least 85 * Both child and parent(s) have adequate German-language skills * Both child and parents consent to intervention sessions being video-recorded

Exclusion criteria

* The participating parent(s) has current symptoms of bipolar disorder, psychotic symptoms, personality disorder, substance addiction, or is suicidal * The participating child meets criteria for a current, or previous, episode of any psychiatric disorder * The participating child is undergoing or has undergone treatment for depression * The participating child or parent have serious symptoms of a disorder (or are in crisis) that may hamper their ability to take part in the study

Design outcomes

Primary

Measure	Time frame	Description
Presence or absence of a depressive episode (child)	T4 (9 months after completion of the programme)	The German version of the Diagnostic Interview for Psychiatric Disorders in Children and Adolescents (Kinder DIPS) will be used to assess whether the child meets the Diagnostic and Statistical Manual of Mental Disorders (DSM-IV) criteria for a depressive episode.

Secondary

Measure	Time frame	Description
Symptoms of depression (child)	Within 2 weeks of the last session of the intervention (T2) as well as 3 months after the intervention (T3) and 9 months after the intervention (T4)	Self-reported symptoms of depression will be collected using the German questionnaires Depression Inventory for Children and Adolescents (DIKJ) and Beck Depression Inventory (BDI-II; depending on the child's age).
Psychopathological symptoms (child)	Within 2 weeks of the last session of the intervention (T2) as well as 3 months after the intervention (T3) and 9 months after the intervention (T4)	More general internal and external psychopathological symptoms will be measured using German versions of the questionnaires Youth Self-Report (YSR; child self-report) and Child Behaviour Checklist (CBCL; parent-report).

Countries

Germany

Outcome results

None listed