Pulmonary Disease, Chronic Obstructive
Conditions
Keywords
Pulmonary disease, chronic obstructive, Downhill walking, exercise
Brief summary
This randomized control trial will investigate whether a modality that generates more contractile muscle fatigue with lower ventilatory requirements render better results after a 12-week exercise training program in subjects with COPD. Subjects will be randomized to either exercise in a training program including downhill walking or to exercise in a training program including conventional walking.
Interventions
Walk on a treadmill with a negative inclination.
Walk on a treadmill without inclination. Possible to progress training intensity with positive inclinations
Sponsors
Research Foundation Flanders
Conselho Nacional de Desenvolvimento Científico e Tecnológico
KU Leuven
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
* Patients with a primary diagnosis of COPD according to internationally accepted guidelines * Patients referred to the outpatient PR program of Gasthuisberg University Hospital(Leuven, Belgium)
Exclusion criteria
* Any underlying disease or musculoskeletal limitation that could impair the ability to perform any of the exercise training modalities * Absence of exacerbations in the previous month before entering the present study * Patients included on the waiting list for lung transplantation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| changes in 6-minute walking distance | changes from baseline to Week 12 |
Countries
Belgium
Contacts
Primary ContactThierry Troosters, PhD
Outcome results
None listed