Prevention of the Procedural Pain in the Newborn
Conditions
Keywords
Breast-feeding, Saccharose, Breast-feeding newborn, cortical pain responses, near infrared spectroscopy (NIRS), Salivary rate cortisol, heel lance
Brief summary
The aim of this study is to compare the impact of two non-medicinal strategies: the breast-feeding and saccharose to measure effects in cerebral cortex during pain using near infrared spectroscopy (NIRS)
Detailed description
Many studies of non-medicinal treatments(saccharose and breast-feeding)show a decrease of expression of pain in newborn. However Slater and al questioned these practices due to the absence of modification of the cerebral answer measured by evoked potential.
Interventions
PROCEDUREsaccharose versus breast-feeding
saccharose versus breast-feeding
Sponsors
University Hospital, Brest
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
37 Weeks to 42 Weeks
Healthy volunteers
No
Inclusion criteria
* Gestationnel age included between 37 and 42 weeks * Born in the CHRU of Brest * Breast-Fed * Score of Apgar upper to 7 * No pathology malformative * Absence of known chromosomal abnormality * Consent of parents
Exclusion criteria
* Maternal drug use * Morphinic treatment * Barbiturate treatment * Benzodiazépine treatment
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Increase of the total concentration of haemoglobin | Measure two minutes before painful gesture, at the moment of painful gesture and 2 minutes after painful gesture. The newborn will be followed for the duration of hospital stay, an expected average of 30 to 60 minutes | Increase of the total concentration of haemoglobin (delta HbT) measured by the spectrometer during the intravenous injection. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Dosage of rate salivary cortisol | before and after painful gesture | Salivary cortisol sampling |
Countries
France
Outcome results
None listed