Delirium
Conditions
Brief summary
The aim of the present study is to assess the effect of postoperative remifentanil infusion on the incidence of emergence agitation in preschool-aged children undergoing strabismus surgery with sevoflurane anaesthesia.
Detailed description
Patients are randomly assigned to one of two groups. Anesthesia is maintained with sevoflurane and remifentanil infusion. All patients received a predetermined concentrations of remifentanil according to their group assignments (control group, remifentanil 0 ug/kg/min; remifentanil group, remifentanil 0.05 ug/kg/min) from 10 minutes before the end of surgery to discharge from postanesthetic care unit. emergence agitation is assessed during the emergence phase.
Interventions
DRUGRemifentanil
Children randomised to remifentanil group receive remifentanil 0.05 ug/kg/min. Children randomised to control group receive normal saline (placebo)
DRUGPlacebo
Sponsors
Yeungnam University College of Medicine
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
DOUBLE (Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
3 Years to 7 Years
Healthy volunteers
No
Inclusion criteria
* American Society of Anesthesiologists physical status I and II * preschool-aged children undergoing strabismus surgery
Exclusion criteria
* psychological disorders * emotional disorders * abnormal cognitive development * developmental delay * allergy to the drugs in our protocol
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| the scale of emergence agitation | up to 30 minutes after arrival in postanesthetic care unit, and 30 minutes after discharge from postanesthetic care unit. | A blinded observer record emergence agitation at just after laryngeal mask removal, 5 minutes after arrival in postanesthetic care unit, 10 minutes after arrival in postanesthetic care unit, 15 minutes after arrival in postanesthetic care unit, 30 minutes after arrival in postanesthetic care unit, and 30 minutes after discharge from postanesthetic care unit. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| the effect of remifentanil on the emergence | up to 30 minutes after the discharge form postanesthetic care unit | A blinded observer record duration of anaesthesia, eye-opening time, time to remove laryngeal mask airway, respiratory depression, nausea, and vomiting at the end of surgery, 5 minutes after arrival in postanesthetic care unit, 10 minutes after arrival in postanesthetic care unit, 15 minutes after arrival in postanesthetic care unit, 30 minutes after arrival in postanesthetic care unit, and 30 minutes after discharge from postanesthetic care unit. |
Countries
South Korea
Contacts
Primary ContactSangjin Park, M.D.
Outcome results
None listed