Blood Loss
Conditions
Keywords
Blood loss, total knee arthroplasty, hot knife, cold knife, unipolar electrocautery, surgical blade
Brief summary
Using of surgical blade may have less blood loss than unipolar electrocautery in Total Knee Arthroplasty (TKA).
Interventions
PROCEDUREsurgical blade
Using surgical blade all the time of surgery
PROCEDUREelectrocautery
Using electrocautery all the time except at skin incision
Sponsors
Thammasat University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
50 Years to 85 Years
Healthy volunteers
No
Inclusion criteria
* osteoarthritis of the knee who undergoing unilateral primary total knee arthroplasty * age 50-85 years old * ASA class 1-3
Exclusion criteria
* unable to perform spinal anaesthesia * history of coagulation disorder * renal impairment (CrCl \<30 mL/min) or cirrhosis * platelet count \< 100,000 or abnormal coagulogram * on pacemaker * stop anti-platelet or anti-coagulogram less than 7 days
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Blood loss | 48 hours | \- detected total blood loss from hemoglobin at 24,48 hours after surgery, maximum Hb drop and blood loss collected in radivac drain |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| inflammation | 48 hours | determine inflammatory response with C-rective protein (CRP) at post-op 48 hours |
| Knee function | 3 months | measured with WOMAC |
| knee range of motion | 3 months | — |
| complication | 2 weeks | detected with wound dehiscence, wound infection |
Countries
Thailand
Outcome results
None listed