Blood Clots, Deep Vein Thrombosis
Conditions
Keywords
Physicians, Genomics, Internal Medicine, Warfarin, Natural History
Brief summary
Background: -How people respond to drugs depends in part on their genes. For some drugs, doctors can use an individuals genetic background to help in dosing the drug. Researchers want to know how doctors incorporate personalized or genomic medicine into clinical practice. Objective: -To study how physicians make personalized treatment decisions Eligibility: -Healthy adult primary care physicians who are internal (or family) medicine residents. Design: * Participants will complete a screening form. * Participants will put on a headset, called a head-mounted display, showing a virtual reality environment. * The environment will contain an exam room and the virtual patient. * After interacting with the virtual patient, participants will complete a series of survey measures. * Participation will last for about 60 minutes. The virtual patient interaction and follow-up questions will be audio taped.
Detailed description
This study will examine factors related to primary care physicians clinical decision-making. Using a virtual clinical interaction experiment, we aim to better understand physicians decision-making processes and to explore their communication behaviors toward patients in the clinical encounter. Physician participants will enter a virtual exam room where they will be asked to respond to a virtual patient, acting as her primary care physician in a follow-up visit to evaluate her for depression. Various aspects of physician communication in the virtual clinic and self-report measures related to decision-making will be analyzed.
Interventions
None listed
Sponsors
National Human Genome Research Institute (NHGRI)
Study design
Observational model
CASE_CONTROL
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
21 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* INCLUSION CRITERIA: * All physicians will be healthy adult volunteers who are medical residents in the internal medicine specialty.
Exclusion criteria
1. persons with seizure or vestibular disorders; 2. persons who are highly prone to motion sickness; 3. those without normal or normal to corrected vision or hearing; 4. all current and past employees and contractors of NHGRI; and 5. persons who have received information about the study purpose or procedure from a past participant. NHGRI employees are excluded for this protocol because they are likely to have specialized genomic knowledge and may think differently about genomics in the clinical interaction.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| To explore how physicians use genetic testing for anticoagulant (warfarin) dosage in patients of different racial/ethnic and SES backgrounds | Outcome measurements are assessed on the same date of the study visit. | To explore how physicians use genetic testing for anticoagulant (warfarin) dosage in patients of different racial /ethnic and SES backgrounds |
Countries
United States
Contacts
PRINCIPAL_INVESTIGATORSusan J Persky, Ph.D.
National Human Genome Research Institute (NHGRI)
Outcome results
None listed