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Multi-Family Group Therapy for Adult Eating Disorders

A Comparison of Family Supportive Counseling and Multi-Family Therapy Group for People With Eating Disorders and Their Family Members: A Randomized Controlled Trial

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT02106728
Acronym
MFGT
Enrollment
117
Registered
2014-04-08
Start date
2012-01-31
Completion date
2015-01-31
Last updated
2016-08-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Eating Disorders

Keywords

Eating Disorders, Family Therapy, Multi-Family Therapy, Bulimia Nervosa, Eating Disorder Not Otherwise Specified

Brief summary

Eating Disorders are a debilitating and serious mental illness. This illness is associated with medical complications, psychological and social impairment. Families of people with an eating disorder also report that they lack resources and have many unmet needs. Families often have insufficient information regarding the eating disorder, available treatment options and strategies for supporting the person with the illness. The purpose of this study is to evaluate the effectiveness of two different family interventions for people with eating disorders and their family members (parents or partners) receiving treatment either in the inpatient or day treatment Eating Disorder Program at the Toronto General Hospital, University Health Network. Family supportive counseling consists of people with eating disorders and their family members meeting with a family therapist. Multi-family group therapy involves eight to ten families who meet as a group with two therapists. The investigators are conducting a study to assess the differences between these two different family interventions. This study will help us identify who benefits the most from participating in family supportive counseling or multi-family therapy. The investigators are also evaluating which intervention is more effective at helping the person with the eating disorder overcome their illness while helping their family members learn how to support the recovery process. Both family therapy interventions are delivered by experienced family therapy clinicians who work in either the Inpatient or Day Treatment Eating Disorder Program at Toronto General Hospital.

Detailed description

Background: Bulimia Nervosa (BN) is a serious and persistent mental illness with a high rate of mortality and morbidity. Research demonstrates that individuals with BN have high drop-out rates, multiple re-admissions to tertiary care programs and high relapse rates all of which may contribute to the chronicity of this illness. A systematic review of randomized controlled trials for eating disorders reveals dropout rates ranging from 0-43%. Individuals with BN are at the highest risk for relapse during the first three months following the completion of inpatient treatment for BN. A higher BMI at completion of an intensive eating disorder program and weight maintenance immediately following treatment are associated with lower relapse rates at six and twelve months. Women with chronic BN have a poorer quality of life than women in the general population in a variety of domains. Individuals with BN have access to a smaller support network outside of their nuclear family compared with normal controls. They are often confronted with negative stereotypes and stigmatizing attitudes from the general public who often perceive affected individuals as having control over their eating behaviours. Fear of being stigmatized and negatively stereotyped, a poor quality of life, a smaller social support network and lower expectations of receiving appropriate support, may contribute to and heighten the reliance of individuals with BN on their immediate families for emotional and instrumental support. The over-reliance on families for support may contribute to duress in families who may be willing to assist the person afflicted with BN but lack the sufficient knowledge and skills to effectively intervene to assist with the significant medical and psychological impairment that results from this illness. Caregivers of individuals with eating disorders experience significant distress poor quality of life, and intense feelings of self-blame and shame as a result of their caregiving role. Caregivers often feel responsible for causing a loved one to develop the illness, and these feelings are often reinforced by professionals. In fact, the general public is more likely to blame families for causing BN compared with other mental illnesses such as schizophrenia. Poor family functioning in families of individuals with BN is predicted by problematic eating symptoms, conflict about how best to support the affected person, stigma and lack of social support. Concerns and fears that their loved one will be discriminated against or labeled negatively have been shown to result in family members withdrawing from their own social support network. Social support has been shown to mitigate caregiver distress and burden and poor health in carers of individuals with mental illnesses. Hence, an intervention is required to increase social support for individuals and their family members while providing educational information that challenges stigma, self-blame and shame. Caring for an adult with chronic BN creates many challenges for the carer, including psychological duress, social isolation, stigma and poor family functioning. In turn, increased family conflict may exacerbate illness behaviours in the person with BN. Due to the emaciated appearance of the person with BN and the life threatening nature of this illness, family members may become overly protective and avoid discussions that may be distressing to the affected individual. Anxiety and depression may further heighten caregiver distress and intensify their propensity to over-protect the affected individual. Family members may also respond to severe symptoms by accommodating to the illness while taking on responsibility for the affected person in ways that are not age-appropriate. Negative feelings may be increased in the carers when their efforts to assist and motivate the person into treatment are met with denial about the seriousness of the illness and ambivalence to engage in treatment. These responses may elicit criticism from carers, especially if they perceive the eating symptoms as volitional. Emotional over-involvement, accommodation and criticism can have negative influences on the person with BN including heightened distress, decreased willingness to seek help and poorer treatment outcomes. An intervention is urgently needed to address the burden that this illness imposes on families and improve the quality of life of the carer, while teaching communication and problem solving skills that facilitate recovery from BN. In the last decade, Multi-family group therapy (MFT) has been recognized internationally as an innovative approach to working with families of BN adolescents and has been shown to contribute to positive outcomes. MFT has also been widely employed and shown to be effective in families of adults affected with other mental illnesses including substance abuse, bipolar disorder and schizophrenia. To date, MFT has not been investigated in families of adults with BN. Given the evidence that demonstrates the efficacy of MFT in adolescent BN and other mental illnesses in adults, the proposed research study seeks to assess the efficacy of MFT for adults with BN and their families. Overview of Proposed Study: In this study, the investigators propose to investigate MFT, which has never before been studied in adults with BN and their carers. The overarching objective will be to conduct a randomized controlled trial comparing MFT with treatment as usual (TAU) in patients receiving intensive treatment for BN and their carers. Hypotheses and Research Questions: This proposed randomized controlled trial aims to provide pilot data regarding the efficacy of Multi-Family Therapy (MFT) in improving treatment outcomes for patients with Bulimia Nervosa (BN) and in reducing caregiver distress. Compared with patients not participating in MFT, the investigators hypothesize that patients with BN and their carers participating in MFT will have: 1) lower drop out rates, 2) higher likelihood of sustaining a body mass index (BMI) of 18.5 or higher at three months post-treatment, 3) greater improvement in general psychological health for carers from pre-treatment to three months post-treatment, and 4) reductions in the adverse impact of caregiving, expressed emotion and accommodation of eating behaviours at three months post-treatment. Finally, the investigators expect that descriptive data will show that MFT is a feasible, acceptable option for patients with BN and their carers.

Interventions

Multi-Family Therapy is conducted once per week over the course of 8 weeks for 1.5 hours per session. Therapy is provided to a minimum of 3 families and a maximum of 6 families with the aid of two to three therapist group leaders. Group topics are set and cover material on eating disorder psychoeducation, care-giving styles, meal support, and relapse prevention.

BEHAVIORALSupportive Family Therapy

Supportive Family Therapy is treatment as usual in the eating disorders program at TGH. Families meet independently with a therapist once per week for 1 hour per session. The length of the therapy and the topics of therapy are decided upon collaboratively with the therapist and the family.

Sponsors

University Health Network, Toronto
CollaboratorOTHER
Gina Dimitropoulos
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
16 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* any patient attending the eating disorders program at University Health Network, Toronto General Hospital and their family members over the age of 16 (siblings, parents, partners).

Exclusion criteria

* current family violence.

Design outcomes

Primary

MeasureTime frameDescription
Dropout3 months post enrollment3 months post enrollment in the study, participant's program completion is measures (completed, withdrawn, dropped out)
Change in WeightBaseline, End of treatment(8 weeks for multi-family therapy/average 10 weeks for supportive family therapy)Change in weight is measured to gauge if there has been a loss, gain, or maintenance.

Secondary

MeasureTime frameDescription
Change in Caregiver FunctioningBaseline, end of treatment(8 weeks for multi-family therapy/average 10 weeks for supportive family therapy), three months post-treatmentEDSIS measures impact of ED.Subscales:Nutrition:0-32;Guilt:0-20;Dysregulated Behaviour:0-28;Social Isolation:0-16;Total: 0-96.Higher scores mean more negative appraisals of caregiving.Scores are summed.2)FQ measures criticism in families. Subscales:Critical Comments: 10-40;Emotional over-involvement: 10-40;Total:20-80.Higher scores mean higher perceived criticism.Scores are summed.3)SPS measures perceived social support. Attachment:4-16;Social Integration:4-16;Reassurance of Worth:4-16;Reliable Alliance Guidance:4-16;Opportunity for Nurturance:4-16;Total:24-96.Higher scores indicate higher social support.Scores are summed.4)Devaluation of consumers and consumer families measures perceived discrimination and stigma. Two subscales are:devaluation of consumers(8-32);devaluation of consumer's families (7-28).Higher scores indicate higher levels of perceived discrimination and stigma. Subscales are summed separately.5)BDI, scored from 0-63:higher scores indicate higher levels of depression

Countries

Canada

Participant flow

Recruitment details

Consecutive patients with Anorexia Nervosa admitted to the Eating Disorder Program between 2011 and 2014, were approached to participate within the first 3 weeks of treatment. Patients shared information about the study with their family members whom they identified as being involved in supporting them.Exclusion factors was current family violence.

Pre-assignment details

Participants were assigned non-randomly to Separated Family Therapy (treatment as usual) or Multi-Family thearpy dependent on treatment availability. MFT was offered four times a year as a closed group. A series of groups would begin once four to six families consented to participate in the study. After a group started, families were offered SFT.

Participants by arm

ArmCount
Multi-Family Therapy
Multi-family group therapy involving eight to ten families who meet as a group with two therapists for a duration of 8, 1.5h sessions. Multi-Family Therapy: Multi-Family Therapy is conducted once per week over the course of 8 weeks for 1.5 hours per session. Therapy is provided to a minimum of 3 families and a maximum of 6 families with the aid of two to three therapist group leaders. Group topics are set and cover material on eating disorder psychoeducation, care-giving styles, meal support, and relapse prevention.
70
Supportive Family Therapy
Family supportive counseling consists of people with eating disorders and their family members meeting with a family therapist. This is treatment as usual in the Eating Disorders Program at University Health Network. Supportive Family Therapy: Supportive Family Therapy is treatment as usual in the eating disorders program at TGH. Families meet independently with a therapist once per week for 1 hour per session. The length of the therapy and the topics of therapy are decided upon collaboratively with the therapist and the family.
47
Total117

Baseline characteristics

CharacteristicMulti-Family TherapySupportive Family TherapyTotal
Age, Categorical
<=18 years
0 Participants0 Participants0 Participants
Age, Categorical
>=65 years
0 Participants0 Participants0 Participants
Age, Categorical
Between 18 and 65 years
70 Participants47 Participants117 Participants
Age, Continuous26.20 years
STANDARD_DEVIATION 7.36
26.20 years
STANDARD_DEVIATION 7.36
26.20 years
STANDARD_DEVIATION 7.36
Diagnosis of Patient Participant Subset
(Anorexia Nervosa (Binge Purge subtype)
13 participants12 participants25 participants
Diagnosis of Patient Participant Subset
Anorexia Nervosa (Restrictive Subtype)
10 participants10 participants20 participants
Region of Enrollment
Canada
70 participants47 participants117 participants
Sex: Female, Male
Female
51 Participants28 Participants79 Participants
Sex: Female, Male
Male
19 Participants19 Participants38 Participants

Adverse events

Event typeEG000
affected / at risk
EG001
affected / at risk
deaths
Total, all-cause mortality
— / —— / —
other
Total, other adverse events
0 / 700 / 47
serious
Total, serious adverse events
0 / 700 / 47

Outcome results

Primary

Change in Weight

Change in weight is measured to gauge if there has been a loss, gain, or maintenance.

Time frame: Baseline, End of treatment(8 weeks for multi-family therapy/average 10 weeks for supportive family therapy)

ArmMeasureGroupValue (MEAN)Dispersion
Multi-Family TherapyChange in WeightPost-Treatment Weight20.29 poundsStandard Deviation 1.41
Multi-Family TherapyChange in WeightPre-Treatment Weight15.68 poundsStandard Deviation 1.61
Supportive Family TherapyChange in WeightPost-Treatment Weight20.29 poundsStandard Deviation 1.41
Supportive Family TherapyChange in WeightPre-Treatment Weight15.68 poundsStandard Deviation 1.61
Primary

Dropout

3 months post enrollment in the study, participant's program completion is measures (completed, withdrawn, dropped out)

Time frame: 3 months post enrollment

ArmMeasureValue (NUMBER)
Multi-Family TherapyDropout17 participants
Supportive Family TherapyDropout18 participants
Secondary

Change in Caregiver Functioning

EDSIS measures impact of ED.Subscales:Nutrition:0-32;Guilt:0-20;Dysregulated Behaviour:0-28;Social Isolation:0-16;Total: 0-96.Higher scores mean more negative appraisals of caregiving.Scores are summed.2)FQ measures criticism in families. Subscales:Critical Comments: 10-40;Emotional over-involvement: 10-40;Total:20-80.Higher scores mean higher perceived criticism.Scores are summed.3)SPS measures perceived social support. Attachment:4-16;Social Integration:4-16;Reassurance of Worth:4-16;Reliable Alliance Guidance:4-16;Opportunity for Nurturance:4-16;Total:24-96.Higher scores indicate higher social support.Scores are summed.4)Devaluation of consumers and consumer families measures perceived discrimination and stigma. Two subscales are:devaluation of consumers(8-32);devaluation of consumer's families (7-28).Higher scores indicate higher levels of perceived discrimination and stigma. Subscales are summed separately.5)BDI, scored from 0-63:higher scores indicate higher levels of depression

Time frame: Baseline, end of treatment(8 weeks for multi-family therapy/average 10 weeks for supportive family therapy), three months post-treatment

ArmMeasureGroupValue (MEAN)Dispersion
Multi-Family TherapyChange in Caregiver FunctioningFamily Questionnaire_over-involvement26.17 units on a scaleStandard Deviation 4.4
Multi-Family TherapyChange in Caregiver FunctioningEating Disorder Symptom Impact Scale_nutrition15.69 units on a scaleStandard Deviation 6.13
Multi-Family TherapyChange in Caregiver FunctioningEating Disorder Symptom Impact Scale_overall35.13 units on a scaleStandard Deviation 15.11
Multi-Family TherapyChange in Caregiver FunctioningDCCFS_consumer15.93 units on a scaleStandard Deviation 3.14
Multi-Family TherapyChange in Caregiver FunctioningSocial Provisions Scale_social integration12.69 units on a scaleStandard Deviation 2.09
Multi-Family TherapyChange in Caregiver FunctioningEating Disorder Symptom Impact Sc_social isolation4.62 units on a scaleStandard Deviation 3.49
Multi-Family TherapyChange in Caregiver FunctioningFamily Questionnaire_criticism19.92 units on a scaleStandard Deviation 4.73
Multi-Family TherapyChange in Caregiver FunctioningEating Disorder Symptom Impact Scale_behaviour4.57 units on a scaleStandard Deviation 4.56
Multi-Family TherapyChange in Caregiver FunctioningDCCFS_family14.25 units on a scaleStandard Deviation 3.87
Multi-Family TherapyChange in Caregiver FunctioningSocial Provisions Scale_nurturance12.55 units on a scaleStandard Deviation 2.46
Multi-Family TherapyChange in Caregiver FunctioningSocial Provisions Scale_overall76.47 units on a scaleStandard Deviation 9.41
Multi-Family TherapyChange in Caregiver FunctioningSocial Provisions Scale_guidance12.76 units on a scaleStandard Deviation 1390
Multi-Family TherapyChange in Caregiver FunctioningSocial Provisions Scale_reliance alliance14.18 units on a scaleStandard Deviation 1.56
Multi-Family TherapyChange in Caregiver FunctioningSocial Provisions Scale_attachment12.31 units on a scaleStandard Deviation 2.49
Multi-Family TherapyChange in Caregiver FunctioningSocial Provisions Scale_reassurance of worth13.02 units on a scaleStandard Deviation 2.07
Multi-Family TherapyChange in Caregiver FunctioningBeck Depression Inventory12.64 units on a scaleStandard Deviation 9.75
Multi-Family TherapyChange in Caregiver FunctioningEating Disorder Symptom Impact Scale_guilt10.12 units on a scaleStandard Deviation 5.24
Supportive Family TherapyChange in Caregiver FunctioningEating Disorder Symptom Impact Scale_overall35.06 units on a scaleStandard Deviation 11.58
Supportive Family TherapyChange in Caregiver FunctioningSocial Provisions Scale_social integration13.10 units on a scaleStandard Deviation 1.57
Supportive Family TherapyChange in Caregiver FunctioningSocial Provisions Scale_overall78.22 units on a scaleStandard Deviation 7.07
Supportive Family TherapyChange in Caregiver FunctioningSocial Provisions Scale_guidance13.34 units on a scaleStandard Deviation 1.9
Supportive Family TherapyChange in Caregiver FunctioningSocial Provisions Scale_attachment12.18 units on a scaleStandard Deviation 2.09
Supportive Family TherapyChange in Caregiver FunctioningSocial Provisions Scale_reliance alliance13.14 units on a scaleStandard Deviation 1.77
Supportive Family TherapyChange in Caregiver FunctioningBeck Depression Inventory10.50 units on a scaleStandard Deviation 7.54
Supportive Family TherapyChange in Caregiver FunctioningEating Disorder Symptom Impact Scale_guilt8.64 units on a scaleStandard Deviation 3.92
Supportive Family TherapyChange in Caregiver FunctioningDCCFS_family13.41 units on a scaleStandard Deviation 2.62
Supportive Family TherapyChange in Caregiver FunctioningEating Disorder Symptom Impact Sc_social isolation5.13 units on a scaleStandard Deviation 3.05
Supportive Family TherapyChange in Caregiver FunctioningEating Disorder Symptom Impact Scale_behaviour3.31 units on a scaleStandard Deviation 3.55
Supportive Family TherapyChange in Caregiver FunctioningDCCFS_consumer14.94 units on a scaleStandard Deviation 3.3
Supportive Family TherapyChange in Caregiver FunctioningEating Disorder Symptom Impact Scale_nutrition18.04 units on a scaleStandard Deviation 5.62
Supportive Family TherapyChange in Caregiver FunctioningSocial Provisions Scale_nurturance11.69 units on a scaleStandard Deviation 2.67
Supportive Family TherapyChange in Caregiver FunctioningFamily Questionnaire_criticism16.80 units on a scaleStandard Deviation 6.2
Supportive Family TherapyChange in Caregiver FunctioningSocial Provisions Scale_reassurance of worth13.29 units on a scaleStandard Deviation 1.6
Supportive Family TherapyChange in Caregiver FunctioningFamily Questionnaire_over-involvement27.06 units on a scaleStandard Deviation 4.28
Multi-Family Therapy (POST)Change in Caregiver FunctioningSocial Provisions Scale_nurturance12.58 units on a scaleStandard Deviation 2.01
Multi-Family Therapy (POST)Change in Caregiver FunctioningDCCFS_family14.84 units on a scaleStandard Deviation 2.57
Multi-Family Therapy (POST)Change in Caregiver FunctioningEating Disorder Symptom Impact Scale_guilt6.67 units on a scaleStandard Deviation 4.99
Multi-Family Therapy (POST)Change in Caregiver FunctioningFamily Questionnaire_over-involvement23.97 units on a scaleStandard Deviation 5.2
Multi-Family Therapy (POST)Change in Caregiver FunctioningEating Disorder Symptom Impact Scale_nutrition9.43 units on a scaleStandard Deviation 6.47
Multi-Family Therapy (POST)Change in Caregiver FunctioningSocial Provisions Scale_overall78.40 units on a scaleStandard Deviation 8.77
Multi-Family Therapy (POST)Change in Caregiver FunctioningBeck Depression Inventory8.68 units on a scaleStandard Deviation 9.92
Multi-Family Therapy (POST)Change in Caregiver FunctioningSocial Provisions Scale_reassurance of worth13.47 units on a scaleStandard Deviation 1.75
Multi-Family Therapy (POST)Change in Caregiver FunctioningSocial Provisions Scale_attachment12.79 units on a scaleStandard Deviation 2.45
Multi-Family Therapy (POST)Change in Caregiver FunctioningSocial Provisions Scale_social integration12.78 units on a scaleStandard Deviation 1.9
Multi-Family Therapy (POST)Change in Caregiver FunctioningEating Disorder Symptom Impact Scale_overall22.28 units on a scaleStandard Deviation 14.7
Multi-Family Therapy (POST)Change in Caregiver FunctioningSocial Provisions Scale_reliance alliance13.68 units on a scaleStandard Deviation 1.37
Multi-Family Therapy (POST)Change in Caregiver FunctioningDCCFS_consumer15.64 units on a scaleStandard Deviation 3.02
Multi-Family Therapy (POST)Change in Caregiver FunctioningEating Disorder Symptom Impact Sc_social isolation3.64 units on a scaleStandard Deviation 3.84
Multi-Family Therapy (POST)Change in Caregiver FunctioningFamily Questionnaire_criticism16.46 units on a scaleStandard Deviation 4.69
Multi-Family Therapy (POST)Change in Caregiver FunctioningEating Disorder Symptom Impact Scale_behaviour2.41 units on a scaleStandard Deviation 2.69
Multi-Family Therapy (POST)Change in Caregiver FunctioningSocial Provisions Scale_guidance13.41 units on a scaleStandard Deviation 1.75
Supportive Family Therapy (POST)Change in Caregiver FunctioningSocial Provisions Scale_attachment12.59 units on a scaleStandard Deviation 1.55
Supportive Family Therapy (POST)Change in Caregiver FunctioningEating Disorder Symptom Impact Scale_overall18.18 units on a scaleStandard Deviation 1.06
Supportive Family Therapy (POST)Change in Caregiver FunctioningSocial Provisions Scale_nurturance11.95 units on a scaleStandard Deviation 2.08
Supportive Family Therapy (POST)Change in Caregiver FunctioningEating Disorder Symptom Impact Scale_guilt5.49 units on a scaleStandard Deviation 3.92
Supportive Family Therapy (POST)Change in Caregiver FunctioningSocial Provisions Scale_reliance alliance13.20 units on a scaleStandard Deviation 1.83
Supportive Family Therapy (POST)Change in Caregiver FunctioningEating Disorder Symptom Impact Sc_social isolation3.32 units on a scaleStandard Deviation 3.15
Supportive Family Therapy (POST)Change in Caregiver FunctioningEating Disorder Symptom Impact Scale_behaviour.95 units on a scaleStandard Deviation 1.38
Supportive Family Therapy (POST)Change in Caregiver FunctioningEating Disorder Symptom Impact Scale_nutrition8.41 units on a scaleStandard Deviation 6.1
Supportive Family Therapy (POST)Change in Caregiver FunctioningFamily Questionnaire_criticism15.08 units on a scaleStandard Deviation 4.25
Supportive Family Therapy (POST)Change in Caregiver FunctioningFamily Questionnaire_over-involvement24.23 units on a scaleStandard Deviation 4.37
Supportive Family Therapy (POST)Change in Caregiver FunctioningSocial Provisions Scale_overall77.41 units on a scaleStandard Deviation 6.27
Supportive Family Therapy (POST)Change in Caregiver FunctioningSocial Provisions Scale_social integration12.89 units on a scaleStandard Deviation 1.51
Supportive Family Therapy (POST)Change in Caregiver FunctioningSocial Provisions Scale_reassurance of worth13.13 units on a scaleStandard Deviation 1.26
Supportive Family Therapy (POST)Change in Caregiver FunctioningDCCFS_consumer15.46 units on a scaleStandard Deviation 2.89
Supportive Family Therapy (POST)Change in Caregiver FunctioningDCCFS_family13.38 units on a scaleStandard Deviation 2.65
Supportive Family Therapy (POST)Change in Caregiver FunctioningBeck Depression Inventory7.52 units on a scaleStandard Deviation 7.52
Supportive Family Therapy (POST)Change in Caregiver FunctioningSocial Provisions Scale_guidance13.21 units on a scaleStandard Deviation 1.79
Multi-Family Therapy (8WEEKS)Change in Caregiver FunctioningFamily Questionnaire_over-involvement21.82 units on a scaleStandard Deviation 5.42
Multi-Family Therapy (8WEEKS)Change in Caregiver FunctioningSocial Provisions Scale_social integration12.98 units on a scaleStandard Deviation 1.64
Multi-Family Therapy (8WEEKS)Change in Caregiver FunctioningFamily Questionnaire_criticism16.38 units on a scaleStandard Deviation 4.18
Multi-Family Therapy (8WEEKS)Change in Caregiver FunctioningBeck Depression Inventory6.12 units on a scaleStandard Deviation 8.34
Multi-Family Therapy (8WEEKS)Change in Caregiver FunctioningSocial Provisions Scale_reassurance of worth13.32 units on a scaleStandard Deviation 1.88
Multi-Family Therapy (8WEEKS)Change in Caregiver FunctioningEating Disorder Symptom Impact Scale_nutrition6.98 units on a scaleStandard Deviation 5.21
Multi-Family Therapy (8WEEKS)Change in Caregiver FunctioningEating Disorder Symptom Impact Scale_behaviour2.03 units on a scaleStandard Deviation 2.66
Multi-Family Therapy (8WEEKS)Change in Caregiver FunctioningDCCFS_consumer15.33 units on a scaleStandard Deviation 2.49
Multi-Family Therapy (8WEEKS)Change in Caregiver FunctioningSocial Provisions Scale_reliance alliance13.53 units on a scaleStandard Deviation 1.56
Multi-Family Therapy (8WEEKS)Change in Caregiver FunctioningEating Disorder Symptom Impact Scale_guilt6.11 units on a scaleStandard Deviation 4.73
Multi-Family Therapy (8WEEKS)Change in Caregiver FunctioningDCCFS_family14.05 units on a scaleStandard Deviation 3.32
Multi-Family Therapy (8WEEKS)Change in Caregiver FunctioningEating Disorder Symptom Impact Scale_overall18.21 units on a scaleStandard Deviation 13.26
Multi-Family Therapy (8WEEKS)Change in Caregiver FunctioningSocial Provisions Scale_guidance12.98 units on a scaleStandard Deviation 1.94
Multi-Family Therapy (8WEEKS)Change in Caregiver FunctioningSocial Provisions Scale_nurturance12.49 units on a scaleStandard Deviation 2.48
Multi-Family Therapy (8WEEKS)Change in Caregiver FunctioningEating Disorder Symptom Impact Sc_social isolation3.17 units on a scaleStandard Deviation 2.69
Multi-Family Therapy (8WEEKS)Change in Caregiver FunctioningSocial Provisions Scale_attachment12.32 units on a scaleStandard Deviation 23.7
Multi-Family Therapy (8WEEKS)Change in Caregiver FunctioningSocial Provisions Scale_overall77.07 units on a scaleStandard Deviation 86.17
Supportive Family Therapy (Approximately 10 WEEKS)Change in Caregiver FunctioningSocial Provisions Scale_nurturance11.83 units on a scaleStandard Deviation 1.51
Supportive Family Therapy (Approximately 10 WEEKS)Change in Caregiver FunctioningBeck Depression Inventory3.77 units on a scaleStandard Deviation 2.72
Supportive Family Therapy (Approximately 10 WEEKS)Change in Caregiver FunctioningEating Disorder Symptom Impact Scale_guilt3.76 units on a scaleStandard Deviation 2.58
Supportive Family Therapy (Approximately 10 WEEKS)Change in Caregiver FunctioningSocial Provisions Scale_social integration12.74 units on a scaleStandard Deviation 1.37
Supportive Family Therapy (Approximately 10 WEEKS)Change in Caregiver FunctioningFamily Questionnaire_criticism12.91 units on a scaleStandard Deviation 2.21
Supportive Family Therapy (Approximately 10 WEEKS)Change in Caregiver FunctioningSocial Provisions Scale_attachment12.07 units on a scaleStandard Deviation 1.68
Supportive Family Therapy (Approximately 10 WEEKS)Change in Caregiver FunctioningEating Disorder Symptom Impact Scale_nutrition6.81 units on a scaleStandard Deviation 3.81
Supportive Family Therapy (Approximately 10 WEEKS)Change in Caregiver FunctioningSocial Provisions Scale_guidance12.84 units on a scaleStandard Deviation 1.48
Supportive Family Therapy (Approximately 10 WEEKS)Change in Caregiver FunctioningFamily Questionnaire_over-involvement19.52 units on a scaleStandard Deviation 3.3
Supportive Family Therapy (Approximately 10 WEEKS)Change in Caregiver FunctioningSocial Provisions Scale_reassurance of worth12.82 units on a scaleStandard Deviation 1.18
Supportive Family Therapy (Approximately 10 WEEKS)Change in Caregiver FunctioningDCCFS_family14.04 units on a scaleStandard Deviation 1.97
Supportive Family Therapy (Approximately 10 WEEKS)Change in Caregiver FunctioningEating Disorder Symptom Impact Scale_behaviour1.57 units on a scaleStandard Deviation 1.63
Supportive Family Therapy (Approximately 10 WEEKS)Change in Caregiver FunctioningEating Disorder Symptom Impact Scale_overall13.94 units on a scaleStandard Deviation 3.76
Supportive Family Therapy (Approximately 10 WEEKS)Change in Caregiver FunctioningSocial Provisions Scale_reliance alliance12.93 units on a scaleStandard Deviation 1.64
Supportive Family Therapy (Approximately 10 WEEKS)Change in Caregiver FunctioningEating Disorder Symptom Impact Sc_social isolation2.20 units on a scaleStandard Deviation 2.34
Supportive Family Therapy (Approximately 10 WEEKS)Change in Caregiver FunctioningSocial Provisions Scale_overall75.77 units on a scaleStandard Deviation 5.1
Supportive Family Therapy (Approximately 10 WEEKS)Change in Caregiver FunctioningDCCFS_consumer14.99 units on a scaleStandard Deviation 2.06

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026