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Hyperbaric Oxygen Therapy and SPECT Brain Imaging in Cerebral Decompression Illness

Hyperbaric Oxygen Therapy and SPECT Brain Imaging in Cerebral Decompression Illness

Status
UNKNOWN
Phases
Phase 1
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT02105194
Enrollment
45
Registered
2014-04-07
Start date
2007-01-31
Completion date
2018-12-31
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cerebral Decompression Illness, All Phases

Keywords

cerebral decompression illness

Brief summary

Chart review of patients who received hyperbaric oxygen therapy for cerebral decompression illness who also underwent SPECT brain blood flow imaging to see if SPECT brain imaging tracks and is consistent with the clinical condition of the patients.

Detailed description

SPECT brain imaging has been shown to be the most sensitive imaging modality for cerebral decompression illness. This study is a retrospective review of the PI's experience using SPECT brain imaging in the diagnosis and treatment of all phases of cerebral decompression illness over the past two decades. The purpose of the study is to see if the functional imaging is consistent with the clinical condition and cognitive testing. Chart review of symptoms, and physical exam findings will be compared before and after treatment to SPECT brain imaging radiological readings to assess concordance.

Interventions

DRUGHyperbaric oxygen therapy

total body exposure to greater than atmospheric pressure oxygen

Sponsors

Harch Hyperbaric Research Foundation
CollaboratorOTHER
Paul G. Harch, M.D.
Lead SponsorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
ALL
Healthy volunteers
No

Inclusion criteria

* All patients in the P.I.'s practice who underwent hyperbaric oxygen therapy for cerebral decompression illness in the previous two decades who also underwent SPECT brain blood flow imaging early in the course of treatment and following completion of hyperbaric oxygen therapy.

Exclusion criteria

* none

Design outcomes

Primary

MeasureTime frameDescription
SPECT brain imagingWithin one month after completion of hyperbaric oxygen therapyComparison of SPECT brain imaging chart copy of radiological reading before or early in the treatment history to SPECT brain imaging chart copy of radiological reading after treatment. Imaging will be scored as better, worse, or no change based on resolution of defects or improvement in pattern of injury.

Secondary

MeasureTime frameDescription
Symptoms of cerebral decompression illnessWithin one month after hyperbaric oxygen therapyChart reports of patients' symptoms of cerebral decompression illness before hyperbaric oxygen therapy will be compared to symptoms after hyperbaric oxygen therapy and rated as better, worse, or no change.
Abnormal physical exam findingsWithin one month after hyperbaric oxygen therapyChart reports of abnormal physical exam findings before hyperbaric oxygen therapy will be compared to chart reports of physical exam findings after hyperbaric oxygen therapy and rated as better, worse, or no change.

Countries

United States

Contacts

Primary ContactPaul G Harch, M.D.
paulharchmd@gmail.com504-309-4948

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026