Melanoma, Non Small Cell Lung Cancer, Small Cell Lung Cancer
Conditions
Brief summary
Lung Cancer and melanoma relapsed frequently whereas its very sensitive to treatment such as chemotherapy or radiotherapy. The purpose of this study is to have a better understanding of why those patients are relapsing using next generation sequencing to identify rare mutations and assessed their predictive value.
Interventions
PROCEDUREBlood sample
Optional
PROCEDURETumorous biopsy
Optional
PROCEDUREHealthy material sample
Optional
Sponsors
Gustave Roussy, Cancer Campus, Grand Paris
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
SCREENING
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
1. Cytological or histological diagnosis of SCLC, NSCLC or melanoma 2. Patients age \>/= 18 years old 3. Indication of treatment using platinum salts for lung cancer except for patient with NSCLC treated by surgery for whom platinum salts is not indicated 4. If a biopsy is proposed, lesion lust be easily accessible 5. Signed informed consent
Exclusion criteria
1. Patients unable to follow the protocol 2. Consent refusal
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Mutation rate on tumorous material | Assessed at the time of inclusion | Assessed at the time of inclusion using tumorous material used for diagnosis |
Countries
France
Contacts
Primary ContactBenjamin Besse, MD
Backup ContactCaroline Robert, MD
Outcome results
None listed