Development of a Mass-spectometry Based Method for Detecting Xenon Application in Humans

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02105077

Enrollment

Registered

2014-04-07

Start date

2014-03-31

Completion date

2014-12-31

Last updated

2015-03-31

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anesthesia

Keywords

xenon, doping, anesthesia, mass spectrometry, surgery

Brief summary

The purpose of this study is to establish a laboratory method to determine from blood samples whether a person has been treated with xenon.

Detailed description

The noble gas xenon is used for general anesthesia in clinical routine. Recent reports indicate that xenon is also used for increasing performance in high-performance sports. The purpose of this study is to establish a method for detecting xenon exposure in humans. In patients undergoing surgery with xenon anesthesia as part of routine hospital care, small blood samples (3ml) will be taken before anesthesia, during anaesthesia and at 1,2, 4, 8, 16, 24, 32, 40 and 48 hours after anesthesia. These blood samples will be analyzed for traces of xenon.

Interventions

DRUGAnesthesia with inhalative application of xenon gas

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Age of 18 years and older * Xenon-based anesthesia as part of routine care

Exclusion criteria

* Inability to give written informed consent * Known pregnancy * Hemoglobin concentration of less than 12g/dl

Design outcomes

Primary

Measure	Time frame
Detection of xenon in patient blood sample by mass spectrometry	Immediately before induction of anesthesia

Countries

Germany

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026