Intraarticular Xylitol Injections for Knee Osteoarthritis

Status

UNKNOWN

Phases

Phase 4

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02104596

Enrollment

Registered

2014-04-04

Start date

2014-05-31

Completion date

Unknown

Last updated

2014-04-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Knee Osteoarthritis

Brief summary

Hypothesis: Intraarticular injections of isotonic Xylitol solution will improve pain in patients with knee osteoarthritis (OA).

Interventions

DEVICEXylitol

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

45 Years to No maximum

Healthy volunteers

Inclusion criteria

* Age over 45 * Tibiofemoral osteoarthritis * OA stage 2-3 on xray * Pain VAS \> 40mm * No NSAIDs for 3 weeks * No analgetics for 38 hours

Exclusion criteria

* Pain VAS \> 80mm * Pain VAS in contralateral knee \> 40mm * Inflammatory arthritis * Severe effusion * Posttraumatic osteoarthritis * Unstable knee * Isolated patellofemoral disease * Paracetamol hypersensitivity

Design outcomes

Primary

Measure	Time frame
Pain - visual analogue scale	3 months

Countries

Israel

Contacts

Primary ContactLeonid Kandel, MD

kandel@hadassah.org.il+97225844500

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026