Chronic Kidney Disease
Conditions
Keywords
Constipation, Rome III criteria, Hemodialysis
Brief summary
The purpose of this study was to evaluate the effect of olive oil and flaxseed oil in the treatment of constipation of patients undergoing hemodialysis.
Interventions
OTHERMineral oil
4 ml daily (adjusted as needed), for 4 weeks
DIETARY_SUPPLEMENTOlive oil
4 ml daily (adjusted as needed), for 4 weeks
DIETARY_SUPPLEMENTFlaxseed oil
4 ml daily (adjusted as needed), for 4 weeks
Sponsors
Fundação de Amparo à Pesquisa do Estado de São Paulo
Federal University of São Paulo
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
TRIPLE (Subject, Caregiver, Investigator)
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Constipated patients by Rome III criteria * Hemodialysis \> 3 months
Exclusion criteria
* Diagnosis of gastrointestinal disease other than constipation * Previous intolerance to the oils used in the study * Cognitive limitations
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Score of constipation symptoms | 1 month | Constipation was diagnosed by the Rome III criterion. The diagnosis consists in the presence, for at least three months, of two or more of the following symptoms: fewer than three evacuations per week, straining on evacuation, lumpy or hard stools, incomplete evacuation, anorectal obstruction and use of manual maneuvers to facilitate evacuation. Each symptom is scored as: 0=never or rarely, 1=sometimes, 2=often, 3=most of the time and 4=always. In the present study, the frequency of the symptoms was considered as a continuous variable and, a final score ranging from 0 to 24 was calculated. Lowest scores were indicative of fewer symptoms of constipation. |
Countries
Brazil
Outcome results
None listed