Anemia
Conditions
Brief summary
The goal of this protocol is to establish a randomized clinical trial comparing the use of cord blood vs. infant blood with the primary outcome of comparing both the absolute hemoglobin concentration and the percent change in hemoglobin concentration from baseline around 24 hours of life.
Interventions
PROCEDUREDrawing admission labs from cord blood
PROCEDUREDrawing admission labs from infant blood
Sponsors
C.R.Darnall Army Medical Center
Walter Reed National Military Medical Center
United States Naval Medical Center, Portsmouth
Madigan Army Medical Center
Tripler Army Medical Center
Capt Alicia Prescott
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
No minimum to 1 Days
Healthy volunteers
No
Inclusion criteria
* Birth weight less than 1200g or Gestational Age less than 30 weeks born at participating medical centers
Exclusion criteria
* No specific
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Absolute hemoglobin concentration | 24 hours of life |
| Percent change in hemoglobin concentration from baseline | 24 hours of life |
Secondary
| Measure | Time frame |
|---|---|
| Use of Vasopressors | Participants will be followed from birth until time of hospital discharge, an expected average of 13 weeks. |
| Hemoglobin concentration at one week of life | one week |
| Number/volume of packed red blood cell (pRBC) transfusions | Participants will be followed from birth until time of hospital discharge, an expected average of 13 weeks |
| Head Ultrasound | Read at 7 Days of life and at hospital discharge which is approximately 13 weeks of age |
| Hemoglobin concentration at time of hospital discharge | Approximately 10 - 16 weeks |
| Number of blood donor exposures | Participants will be followed from birth until time of hospital discharge, an expected average of 13 weeks. |
Countries
United States
Outcome results
None listed