Evaluation of Short-term Effects of Tourniquet Use in Different Ways During Total Knee Arthroplasty

Evaluation of Short-term Effects of Tourniquet Use in Different Ways During Total Knee Arthroplasty: a Randomized Controlled Trial

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02102581

Enrollment

Registered

2014-04-03

Start date

2011-02-28

Completion date

2011-12-31

Last updated

2014-04-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Osteoarthritis

Keywords

Tourniquet, Total knee arthroplasty, Blood loss, Limb swelling, Limb circumference

Brief summary

To study the short-term effects of tourniquet use in different ways in total knee arthroplasty,60 patients were randomly divided into 2 groups (30 cases/group): group A using the tourniquet throughout the operation, and group B using the tourniquet starting from the implantation of prosthesis to the completion of the operation. Operation time, total measured blood loss, intraoperative transfusion volume, and complication were recorded. Hemoglobin level was recorded preoperatively and in postoperative 1, 3, 7 and 14 days, and the limb circumference, pain score, and knee joint range of motion were also recorded preoperatively and in postoperative 3,7 and 14 days.Investigators want to observe the difference between the two groups. Hypothesis was made that patients in group B may feel better after operation for short time use of tourniquet.

Detailed description

Objective: To study the short-term effects of tourniquet use in different ways in total knee arthroplasty. Methods: 60 patients were randomly divided into 2 groups (30 cases/group): group A using the tourniquet throughout the operation, and group B using the tourniquet starting from the implantation of prosthesis to the completion of the operation. Operation time, total measured blood loss, intraoperative transfusion volume, and complication were recorded. Hemoglobin level was recorded preoperatively and in postoperative 1, 3, 7 and 14 days, and the limb circumference, pain score, and knee joint range of motion were also recorded preoperatively and in postoperative 3,7 and 14 days.

Interventions

PROCEDUREshort time tourniquet

short time tourniquet: the tourniquet starting from the implantation of prosthesis to the completion of the operation.

Study design

Observational model

CASE_CONTROL

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Healthy volunteers

Inclusion criteria

* Patients eligible for the study included those who underwent initial unilateral TKA for osteoarthritis or rheumatoid arthritis.

Exclusion criteria

* Patients with diabetes, hemorrhagic disease, Hb \< 100 g/L, peripheral neurovascular disease, malignant tumors, history of vascular thrombosis, or history of infection in the lower limb were excluded

Design outcomes

Primary

Measure	Time frame
the limb circumference at 10 cm above the knee at postoperative day 1,3,7 and 14	14 days after the surgery

Countries

China

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 19, 2026