Effect of Protocolized Sedation on Days of Mechanical Ventilation in the ICU
Conditions
Keywords
sedatives, analgesics, protocol, mechanical ventilation, analgosedation
Brief summary
The purpose of this study is to evaluate how the investigators provide sedation (medicine that make you sleepy) in the investigators intensive care unit (ICU). This study will look at a new way of using sedation in the ICU to see what effect it has on patients and if it decreases the amount of time spent on mechanical ventilation (machine that breathes for you), and in the ICU.
Interventions
OTHERSedation protocol
Nursing driven sedation protocol
Sponsors
Tampa General Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
HEALTH_SERVICES_RESEARCH
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 100 Years
Healthy volunteers
No
Inclusion criteria
* Patients 18 years of age and older * Patients expected to require mechanical ventilation for greater than 48 hrs
Exclusion criteria
* Need for continuous neuromuscular blockade * Severe chronic neurocognitive dysfunction * Tracheostomy at the time of study enrollment * Alcohol withdrawal risk or symptoms * Drug overdose * Chronic use of narcotics * Active seizures
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Days on mechanical ventilation | Participants will be assessed daily for the duration of their stay in the ICU, an expected average of 4-5 days |
Secondary
| Measure | Time frame |
|---|---|
| ICU Length of stay | Participants will be followed for the entire length of their ICU stay, expected average of 4-7 days |
| 28 day mortality | Participants will be followed for 28 days from enrollment into the study |
Countries
United States
Outcome results
None listed