Stroke
Conditions
Brief summary
Stroke is one of the leading causes of disability, with an estimated prevalence of 50,000 cases per year in Canada. Less than half of stroke patients regain use of their arm and hand. There is currently no intervention regime that is the gold standard, despite the variety of therapeutic techniques used to treat the upper extremity post-stroke. The use of external feedback to improve motor learning is a technique that has been less studied but shows promise. Therefore, the purpose of this proof of principle study it to test whether different auditory feedback frequencies can facilitate reaching ability in people with stroke. In addition brain scans will be collected that will enable us to determine how stroke severity may impact on one's ability to improve with this technique. We hypothesize that patients who receive less feedback (50% alternate) will have enhanced learning relative to the patients who receive more feedback (100%).
Interventions
BEHAVIORALAuditory Feedback 100%
Patients will receive constant auditory feedback across training trials.
BEHAVIORALAuditory Feedback 50% alternate
Patients will receive alternating auditory feedback (1 trial auditory feedback; 1 trial no auditory feedback) across trials
Sponsors
Sunnybrook Health Sciences Centre
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
BASIC_SCIENCE
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
30 Years to 85 Years
Healthy volunteers
Yes
Inclusion criteria
* Unilateral first time MCA ischemic stroke * Stroke patients should have some movement of shoulder/elbow (no movement of hand - e.g. hand, fingers - is OK) * \> 2 months post * between 30-85 years
Exclusion criteria
* prior stroke * severe comprehension (or cognitive) deficit that compromises informed consent or understanding of instructions * contraindications to MRI (e.g. claustrophobia, metal implants) * neurodegenerative or psychiatric disease * apraxia * auditory deficits that would impair testing * prior musculoskeletal injury to back or upper extremity (including shoulder subluxation from stroke) * skin conditions that would preclude taping of goniometers
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in movement error from baseline | participants will be followed for the duration of the study, an expected 3 hours per day for 2 weeks (5 days per week/10 days total) |
Secondary
| Measure | Time frame |
|---|---|
| Change in range of motion | participants will be followed for the duration of the study, an expected 3 hours per day for 2 weeks (5 days per week/10 days total) |
| Change in movement duration | participants will be followed for the duration of the study, an expected 3 hours per day for 2 weeks (5 days per week/10 days total) |
Countries
Canada
Contacts
Primary ContactTea Lulic, MSc
Outcome results
None listed