Endometriosis, Hyperprolactinemia, Polycystic Ovary Syndrome
Conditions
Keywords
menstrual cycle dynamics, PCOS, hyperprolactinemia, endometriosis, infertility
Brief summary
Development of a bio-mathematical model of the human female cycle
Detailed description
From hormonal measurements throughout 1-2 menstrual cycles in women with and without endocrinological pathology a mathematical model of the human menstrual cycle will be generated. The model will serve to predict development of the cycle including ovulation as well as to better understand the pathophysiology of endocrinological disorder. In a second step current treatment protocols for fertility treatment will be integrated into the model in order to optimize treatment outcome.
Interventions
OTHERFertility treatment
Fertility treatment
Sponsors
University of Zurich
Study design
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
FEMALE
Age
18 Months to 43 Years
Healthy volunteers
Yes
Inclusion criteria
\- Women during their reproductive phase, no hormonal therapy
Exclusion criteria
\- Amenorrhoae
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Hormonal parameters | 3 years | Development of a mathematical model of the menstrual cycle |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Dynamics of fertility treatment | 2 years | Mathematical model to improve fertility treatments |
Other
| Measure | Time frame | Description |
|---|---|---|
| Dynamics of gyneco-endocrinological diseases | 3 years | To better understand the pathophysiological mechanisms in endocrinological diseases |
Countries
Switzerland
Outcome results
None listed