Myopia
Conditions
Brief summary
The objective of the study is to compare the overall subjective preference of filcon II 3 daily disposable silicone hyrogel contact lenses compared to etafilcon A and nelfilcon A daily disposable conventional hydrogel contact lenses.
Detailed description
Double-masked, randomised, controlled crossover trial. Subjects were randomized to wear one or the other of the conventional hydriogel lenses; all subjects wore the filcon II 3 lenses. The first randomly assigned lens type was worn for 3 days, with daily replacement, followed by 3 days of wear of the other lens type, with daily replacement.
Interventions
DEVICEfilcon II 3
Participants wear a first pair of lenses for three days and then crossover and wear a second pair of lenses for three days.
DEVICEetafilcon A
Participants wear a first pair of lenses for three days and then crossover and wear a second pair of lenses for three days.
DEVICEnelfilcon A
Participants wear a first pair of lenses for three days and then crossover and wear a second pair of lenses for three days.
Sponsors
CooperVision, Inc.
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
OTHER
Masking
DOUBLE (Subject, Investigator)
Eligibility
Sex/Gender
ALL
Age
18 Years to 40 Years
Healthy volunteers
No
Inclusion criteria
* Is between 18 and 40 years of age (inclusive) * Has had a self-reported visual exam in the last two years * Is an adapted soft CL wearer * Must be able to wear their lenses at least 3 full days, 10 hours per day, assuming there are no contraindications for doing so * Has a CL spherical prescription between - 1.00 and - 6.00 (inclusive) * Has less than 1.25 D spectacle cylinder in each eye. * Baseline vision of 20/40 or better (in each eye) with their habitual vision correction or 20/20 best-corrected. * Is correctable to at least 20/25 distance visual acuity with study contact lenses in each eye * Has clear corneas and no active ocular disease * Has read, understood and signed the information consent letter * Is willing to comply with the wear schedule (at least 3 full days) * Is willing to comply with the visit schedule
Exclusion criteria
* Has never worn contact lenses before. * Currently wears rigid gas permeable contact lenses. * Has a history of not achieving comfortable CL wear (3 days per week; \> 8 hours/day) * Has a CL prescription outside the range of - 1.00 to -6.00D * Has a spectacle cylinder greater than -1.25D of cylinder in either eye. * Has best corrected spectacle distance vision worse then 20/25 in either eye. * Has any systemic disease affecting ocular health. * Is using any systemic or topical medications, (includes rewetting drops, artificial tears and allergy drops), that will affect ocular health. Occasional use is acceptable but not during the trial. * Has any ocular pathology or severe insufficiency of lacrimal secretion * Has persistent, clinically significant corneal or conjunctival staining * Has active neovascularization or any central corneal scars. * Is aphakic. * Is presbyopic. * Has undergone corneal refractive surgery. * Is participating in any other type of eye related clinical or research study.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Overall Lens Preference - All Study Lenses | Study Exit | Participant's subjective response for overall lens preference after 3 days of daily disposable wear of each pair of lenses. Surveyed at exit. (4 possible ratings: Strongly prefer pair#1, Slightly prefer pair #1, Slightly prefer pair #2, Strongly prefer pair #2). |
| Overall Lens Preference - Hydrogel vs. Filcon II 3 | Study Exit | Participant's subjective response for overall lens preference after 3 days of daily disposable wear of each pair. Surveyed at exit. (4 possible ratings: Strongly prefer pair#1, Slightly prefer pair #1, Slightly prefer pair #2, Strongly prefer pair #2). |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Subjective Response for Vision | Baseline and 3 day follow-up | Participant's subjective response for vision measured at baseline and at 3 day follow-up of daily disposable wear of lenses. (Vision Scale 0-100, 0=very blurry, 100=very clear). |
| Subjective Response for Insertion | Baseline | Participant's subjective response for insertion measured at baseline. (Insertion Handling Scale 0-100, 0=very hard to handle, 100=very easy to handle). |
| Subjective Response for Handling (Insertion and Removal) | 3 days follow-up | Participant's subjective response for handling (insertion and removal) measured at 3 day follow-up of daily disposable wear of lenses. (Handling Scale 0-100, 0=very hard to handle, 100=very easy to handle). |
| Subjective Response for Dryness | 3 Days Follow-up | Participant's subjective response for dryness, measured at baseline and after 3 day follow-up of daily disposable wear of lenses. (Dryness Scale 0-100, 0=Cannot be worn/extremely dry, 100=no dryness experienced at any time). |
| Overall Satisfaction, Vision | 3 Days Follow-up | Participant's subjective response for overall vision satisfaction. Measured after 3 days daily disposable wear of lenses. (4 point Likert Scale; Completely Satisfied, Somewhat Satisfied, Somewhat Dissatisfied, Completely Dissatisfied. |
| Overall Satisfaction, Handling | 3 Days | Participant's subjective response for overall handling satisfaction. Measured after 3 days of daily disposable lens wear. (4 point Likert Scale; Completely Satisfied, Somewhat Satisfied, Somewhat Dissatisfied, Completely Dissatisfied. |
| Overall Satisfaction, Dryness | 3 Days Follow-up | Participant's subjective response for overall dryness satisfaction. Measured after 3 days daily disposable wear of lenses. (4 point Likert Scale; Completely Satisfied, Somewhat Satisfied, Somewhat Dissatisfied, Completely Dissatisfied. |
| Overall Satisfaction, Comfort | 3 Days Follow-up | Participant's subjective response for overall comfort satisfaction. Measured after 3 days daily disposable wear of lenses. (4 point Likert Scale; Completely Satisfied, Somewhat Satisfied, Somewhat Dissatisfied, Completely Dissatisfied. |
| Lens Fit and Performance - Wettability (Baseline and 3 Days Follow-up) | Baseline and 3 days follow-up | The investigator's objective assessment for contact lens fit and performance - wettability. Measured at baseline (10-15mins settling) for both study pairs. Wettability (scale 0-4, 0.25 steps, 0=excellent, 4 severely reduced). |
| Lens Fit and Performance - Deposits (Baseline and 3 Days Follow-up) | Baseline and 3 days follow-up | The investigator's objective assessment for contact lens fit and performance - deposits. Measured at baseline (10-15mins settling) for both study pairs. Deposits (scale 0-4, 0.25 steps, 0=excellent, 4 severely reduced); |
| Lens Fit and Performance - Debris (Baseline and 3 Day Follow-up) | Baseline and 3 day follow-up | The investigator's objective assessment for contact lens fit and performance - debris. Measured at baseline (10-15mins settling) for both study pairs. (Debris scale 0-4; 0.25 steps; 0=no debris, 4=significant debris) |
| Lens Fit and Performance - Movement (Baseline and 3 Days Follow-up) | Baseline and 3 days follow-up | The investigator's objective assessment for contact lens fit and performance - movement. Measured at baseline (10-15mins settling) for both study pairs. Movement (scale in millimeters). |
| Lens Fit and Performance - Fit Acceptance | Baseline and 3 day follow-up | The investigator's objective assessment for contact lens fit and performance - fit acceptance. Measured at baseline and 3 day follow-up (10-15mins settling) for both study pairs. Fit acceptance (Scale 0-4, 0.25 steps, 0=Should not be worn, 4=Perfect). |
| Lens Fit and Performance - Tightness (Baseline and 3 Day Follow-up) | Baseline and 3 day follow-up | The investigator's objective assessment for contact lens fit and performance - tightness. Measured at baseline (10-15mins settling) for both study pairs. Tightness (Scale 0-4, 0.25 steps, 0=Should not be worn, 4=Perfect). |
| Ocular Health - Biomicroscopy | 3 Days Follow-up | The investigator's objective assessment of ocular health assessed for each study Pair after 3 days wear by biomicroscopy. Bulbar and Limbal Hyperemia; Corneal Staining Type, Extent and Depth, Conjunctival Staining and Indentation. BrienHolden Vision Institute Continuous Scale: 1-4, 0.5 steps (1=Very, 2=Slight, 3=Moderate, 4=Severe) |
| Overall Satisfaction | 3 Days Follow-up | Participant's subjective response for overall satisfaction. Measured after 3 days of daily disposable lens wear. (4 point Likert Scale; Completely Satisfied, Somewhat Satisfied, Somewhat Dissatisfied, Completely Dissatisfied. |
| Subjective Response for Comfort | Baseline and 3 day follow-up | Participant's subjective response for comfort measured at baseline and 3 day follow-up. (Continuous Comfort Scale 0-100, 0=cannot be worn/causes pain, 100=cannot be felt ever) |
Countries
United States
Participant flow
Recruitment details
Single center evaluation. Thirty five subjects were recruited and 30 subjects completed the trial.
Pre-assignment details
Three participants were enrolled in the study but did not meet inclusion criteria, therefore discontinued before lens randomization.
Participants by arm
| Arm | Count |
|---|---|
| Etafilcon A, Then Filcon II 3 Participants wear a first pair of lenses for three days and then crossover and wear a second pair of lenses for three days.
etafilcon A: contact lens filcon II 3: contact lens | 14 |
| Nelfilcon A, Then Filcon II 3 Participants wear a first pair of lenses for three days and then crossover and wear a second pair of lenses for three days.
nelfilcon A: contact lens filcon II 3: contact lens | 16 |
| Total | 30 |
Withdrawals & dropouts
| Period | Reason | FG000 | FG001 |
|---|---|---|---|
| First Intervention (3 Days) | Lost to Follow-up | 1 | 0 |
| First Intervention (3 Days) | Visual Acuity | 0 | 1 |
Baseline characteristics
| Characteristic | Etafilcon A, Then Filcon II 3 | Nelfilcon A, Then Filcon II 3 | Total |
|---|---|---|---|
| Age, Continuous | 21.5 years STANDARD_DEVIATION 4.9 | 21.2 years STANDARD_DEVIATION 5 | 21.4 years STANDARD_DEVIATION 5 |
| Sex: Female, Male Female | 12 Participants | 14 Participants | 26 Participants |
| Sex: Female, Male Male | 2 Participants | 2 Participants | 4 Participants |
Adverse events
| Event type | EG000 affected / at risk | EG001 affected / at risk | EG002 affected / at risk |
|---|---|---|---|
| deaths Total, all-cause mortality | — / — | — / — | — / — |
| other Total, other adverse events | 1 / 16 | 0 / 14 | 0 / 30 |
| serious Total, serious adverse events | 0 / 16 | 0 / 14 | 0 / 30 |
Outcome results
Primary
Overall Lens Preference - All Study Lenses
Participant's subjective response for overall lens preference after 3 days of daily disposable wear of each pair of lenses. Surveyed at exit. (4 possible ratings: Strongly prefer pair#1, Slightly prefer pair #1, Slightly prefer pair #2, Strongly prefer pair #2).
Time frame: Study Exit
Population: Subjects were randomized to wear one or the other of the conventional hydrogel lenses; all subjects wore the Clariti silicone hydrogel lenses.
| Arm | Measure | Group | Value (NUMBER) |
|---|---|---|---|
| Nelfilcon A | Overall Lens Preference - All Study Lenses | Strongly Prefer | 5 participants |
| Nelfilcon A | Overall Lens Preference - All Study Lenses | Slightly Prefer | 4 participants |
| Etafilcon A | Overall Lens Preference - All Study Lenses | Strongly Prefer | 3 participants |
| Etafilcon A | Overall Lens Preference - All Study Lenses | Slightly Prefer | 3 participants |
| Filcon II 3 | Overall Lens Preference - All Study Lenses | Strongly Prefer | 8 participants |
| Filcon II 3 | Overall Lens Preference - All Study Lenses | Slightly Prefer | 7 participants |
Primary
Overall Lens Preference - Hydrogel vs. Filcon II 3
Participant's subjective response for overall lens preference after 3 days of daily disposable wear of each pair. Surveyed at exit. (4 possible ratings: Strongly prefer pair#1, Slightly prefer pair #1, Slightly prefer pair #2, Strongly prefer pair #2).
Time frame: Study Exit
Population: 30 subjects
| Arm | Measure | Group | Value (NUMBER) |
|---|---|---|---|
| Nelfilcon A | Overall Lens Preference - Hydrogel vs. Filcon II 3 | Strongly Prefer | 8 participants |
| Nelfilcon A | Overall Lens Preference - Hydrogel vs. Filcon II 3 | Slightly Prefer | 7 participants |
| Etafilcon A | Overall Lens Preference - Hydrogel vs. Filcon II 3 | Strongly Prefer | 8 participants |
| Etafilcon A | Overall Lens Preference - Hydrogel vs. Filcon II 3 | Slightly Prefer | 7 participants |
Secondary
Lens Fit and Performance - Debris (Baseline and 3 Day Follow-up)
The investigator's objective assessment for contact lens fit and performance - debris. Measured at baseline (10-15mins settling) for both study pairs. (Debris scale 0-4; 0.25 steps; 0=no debris, 4=significant debris)
Time frame: Baseline and 3 day follow-up
| Arm | Measure | Group | Value (MEAN) | Dispersion |
|---|---|---|---|---|
| Nelfilcon A | Lens Fit and Performance - Debris (Baseline and 3 Day Follow-up) | Baseline | 0.0 units on a scale | Standard Deviation 0 |
| Nelfilcon A | Lens Fit and Performance - Debris (Baseline and 3 Day Follow-up) | 3 days follow up | 0.0 units on a scale | Standard Deviation 0 |
| Etafilcon A | Lens Fit and Performance - Debris (Baseline and 3 Day Follow-up) | Baseline | 0.0 units on a scale | Standard Deviation 0 |
| Etafilcon A | Lens Fit and Performance - Debris (Baseline and 3 Day Follow-up) | 3 days follow up | 0.0 units on a scale | Standard Deviation 0 |
| Filcon II 3 | Lens Fit and Performance - Debris (Baseline and 3 Day Follow-up) | Baseline | 0.0 units on a scale | Standard Deviation 0 |
| Filcon II 3 | Lens Fit and Performance - Debris (Baseline and 3 Day Follow-up) | 3 days follow up | 0.1 units on a scale | Standard Deviation 0.6 |
Secondary
Lens Fit and Performance - Deposits (Baseline and 3 Days Follow-up)
The investigator's objective assessment for contact lens fit and performance - deposits. Measured at baseline (10-15mins settling) for both study pairs. Deposits (scale 0-4, 0.25 steps, 0=excellent, 4 severely reduced);
Time frame: Baseline and 3 days follow-up
| Arm | Measure | Group | Value (MEAN) | Dispersion |
|---|---|---|---|---|
| Nelfilcon A | Lens Fit and Performance - Deposits (Baseline and 3 Days Follow-up) | Baseline | 0.0 units on a scale | Standard Deviation 0 |
| Nelfilcon A | Lens Fit and Performance - Deposits (Baseline and 3 Days Follow-up) | 3 days follow up | 0.0 units on a scale | Standard Deviation 0 |
| Etafilcon A | Lens Fit and Performance - Deposits (Baseline and 3 Days Follow-up) | Baseline | 0.1 units on a scale | Standard Deviation 0.3 |
| Etafilcon A | Lens Fit and Performance - Deposits (Baseline and 3 Days Follow-up) | 3 days follow up | 0.0 units on a scale | Standard Deviation 0 |
| Filcon II 3 | Lens Fit and Performance - Deposits (Baseline and 3 Days Follow-up) | Baseline | 0.0 units on a scale | Standard Deviation 0 |
| Filcon II 3 | Lens Fit and Performance - Deposits (Baseline and 3 Days Follow-up) | 3 days follow up | 0.0 units on a scale | Standard Deviation 0 |
Secondary
Lens Fit and Performance - Fit Acceptance
The investigator's objective assessment for contact lens fit and performance - fit acceptance. Measured at baseline and 3 day follow-up (10-15mins settling) for both study pairs. Fit acceptance (Scale 0-4, 0.25 steps, 0=Should not be worn, 4=Perfect).
Time frame: Baseline and 3 day follow-up
| Arm | Measure | Group | Value (MEAN) | Dispersion |
|---|---|---|---|---|
| Nelfilcon A | Lens Fit and Performance - Fit Acceptance | Baseline | 3.6 units on a scale | Standard Deviation 0.2 |
| Nelfilcon A | Lens Fit and Performance - Fit Acceptance | 3 days follow up | 3.6 units on a scale | Standard Deviation 0.3 |
| Etafilcon A | Lens Fit and Performance - Fit Acceptance | Baseline | 3.6 units on a scale | Standard Deviation 0.2 |
| Etafilcon A | Lens Fit and Performance - Fit Acceptance | 3 days follow up | 3.6 units on a scale | Standard Deviation 0.2 |
| Filcon II 3 | Lens Fit and Performance - Fit Acceptance | Baseline | 3.7 units on a scale | Standard Deviation 0.2 |
| Filcon II 3 | Lens Fit and Performance - Fit Acceptance | 3 days follow up | 3.7 units on a scale | Standard Deviation 0.2 |
Secondary
Lens Fit and Performance - Movement (Baseline and 3 Days Follow-up)
The investigator's objective assessment for contact lens fit and performance - movement. Measured at baseline (10-15mins settling) for both study pairs. Movement (scale in millimeters).
Time frame: Baseline and 3 days follow-up
| Arm | Measure | Group | Value (MEAN) | Dispersion |
|---|---|---|---|---|
| Nelfilcon A | Lens Fit and Performance - Movement (Baseline and 3 Days Follow-up) | Baseline | 0.3 units on a scale | Standard Deviation 0.2 |
| Nelfilcon A | Lens Fit and Performance - Movement (Baseline and 3 Days Follow-up) | 3 days follow up | 0.2 units on a scale | Standard Deviation 0.2 |
| Etafilcon A | Lens Fit and Performance - Movement (Baseline and 3 Days Follow-up) | Baseline | 0.3 units on a scale | Standard Deviation 0.2 |
| Etafilcon A | Lens Fit and Performance - Movement (Baseline and 3 Days Follow-up) | 3 days follow up | 0.3 units on a scale | Standard Deviation 0.2 |
| Filcon II 3 | Lens Fit and Performance - Movement (Baseline and 3 Days Follow-up) | Baseline | 0.3 units on a scale | Standard Deviation 0.1 |
| Filcon II 3 | Lens Fit and Performance - Movement (Baseline and 3 Days Follow-up) | 3 days follow up | 0.3 units on a scale | Standard Deviation 0.2 |
Secondary
Lens Fit and Performance - Tightness (Baseline and 3 Day Follow-up)
The investigator's objective assessment for contact lens fit and performance - tightness. Measured at baseline (10-15mins settling) for both study pairs. Tightness (Scale 0-4, 0.25 steps, 0=Should not be worn, 4=Perfect).
Time frame: Baseline and 3 day follow-up
| Arm | Measure | Group | Value (MEAN) | Dispersion |
|---|---|---|---|---|
| Nelfilcon A | Lens Fit and Performance - Tightness (Baseline and 3 Day Follow-up) | Baseline | 54.0 units on a scale | Standard Deviation 12 |
| Nelfilcon A | Lens Fit and Performance - Tightness (Baseline and 3 Day Follow-up) | 3 days follow up | 58.0 units on a scale | Standard Deviation 12 |
| Etafilcon A | Lens Fit and Performance - Tightness (Baseline and 3 Day Follow-up) | Baseline | 56.0 units on a scale | Standard Deviation 11 |
| Etafilcon A | Lens Fit and Performance - Tightness (Baseline and 3 Day Follow-up) | 3 days follow up | 55 units on a scale | Standard Deviation 12 |
| Filcon II 3 | Lens Fit and Performance - Tightness (Baseline and 3 Day Follow-up) | Baseline | 53.0 units on a scale | Standard Deviation 12 |
| Filcon II 3 | Lens Fit and Performance - Tightness (Baseline and 3 Day Follow-up) | 3 days follow up | 54 units on a scale | Standard Deviation 11 |
Secondary
Lens Fit and Performance - Wettability (Baseline and 3 Days Follow-up)
The investigator's objective assessment for contact lens fit and performance - wettability. Measured at baseline (10-15mins settling) for both study pairs. Wettability (scale 0-4, 0.25 steps, 0=excellent, 4 severely reduced).
Time frame: Baseline and 3 days follow-up
| Arm | Measure | Group | Value (MEAN) | Dispersion |
|---|---|---|---|---|
| Nelfilcon A | Lens Fit and Performance - Wettability (Baseline and 3 Days Follow-up) | Baseline | 3.5 units on a scale | Standard Deviation 0.3 |
| Nelfilcon A | Lens Fit and Performance - Wettability (Baseline and 3 Days Follow-up) | 3 days follow up | 3.6 units on a scale | Standard Deviation 0.2 |
| Etafilcon A | Lens Fit and Performance - Wettability (Baseline and 3 Days Follow-up) | Baseline | 3.3 units on a scale | Standard Deviation 0.5 |
| Etafilcon A | Lens Fit and Performance - Wettability (Baseline and 3 Days Follow-up) | 3 days follow up | 3.2 units on a scale | Standard Deviation 0.6 |
| Filcon II 3 | Lens Fit and Performance - Wettability (Baseline and 3 Days Follow-up) | Baseline | 3.4 units on a scale | Standard Deviation 0.4 |
| Filcon II 3 | Lens Fit and Performance - Wettability (Baseline and 3 Days Follow-up) | 3 days follow up | 3.5 units on a scale | Standard Deviation 0.4 |
Secondary
Ocular Health - Biomicroscopy
The investigator's objective assessment of ocular health assessed for each study Pair after 3 days wear by biomicroscopy. Bulbar and Limbal Hyperemia; Corneal Staining Type, Extent and Depth, Conjunctival Staining and Indentation. BrienHolden Vision Institute Continuous Scale: 1-4, 0.5 steps (1=Very, 2=Slight, 3=Moderate, 4=Severe)
Time frame: 3 Days Follow-up
Population: Only right eye data shown. Left eye data virtually identical. One subject had non-contact lens related adverse event in the nelfilcon A group. Subject temporarily discontinued and went on to complete the study.
| Arm | Measure | Group | Value (MEAN) | Dispersion |
|---|---|---|---|---|
| Nelfilcon A | Ocular Health - Biomicroscopy | Bulbar Hyperemia (Temporal) | 0.81 units on a scale | Standard Deviation 0.3 |
| Nelfilcon A | Ocular Health - Biomicroscopy | Corneal Staining Depth (Superior) | .025 units on a scale | Standard Deviation 0.5 |
| Nelfilcon A | Ocular Health - Biomicroscopy | Corneal Staining Type (Superior) | 0.34 units on a scale | Standard Deviation 0.7 |
| Nelfilcon A | Ocular Health - Biomicroscopy | Limbal Hyperemia (Superior) | 0.38 units on a scale | Standard Deviation 0.4 |
| Nelfilcon A | Ocular Health - Biomicroscopy | Corneal Staining Depth (Temporal) | 0.13 units on a scale | Standard Deviation 0.3 |
| Nelfilcon A | Ocular Health - Biomicroscopy | Corneal Staining Type (Inferior) | 0.50 units on a scale | Standard Deviation 1 |
| Nelfilcon A | Ocular Health - Biomicroscopy | Conjunctival Indent (Nasal) | 0.00 units on a scale | Standard Deviation 0 |
| Nelfilcon A | Ocular Health - Biomicroscopy | Corneal Staining Depth (Nasal) | 0.06 units on a scale | Standard Deviation 0.3 |
| Nelfilcon A | Ocular Health - Biomicroscopy | Corneal Staining Extent (Central) | 0.00 units on a scale | Standard Deviation 0 |
| Nelfilcon A | Ocular Health - Biomicroscopy | Bulbar Hyperemia (Superior) | 0.63 units on a scale | Standard Deviation 0.4 |
| Nelfilcon A | Ocular Health - Biomicroscopy | Corneal Staining Depth (Central) | 0.00 units on a scale | Standard Deviation 0 |
| Nelfilcon A | Ocular Health - Biomicroscopy | Corneal Staining Extent (Nasal) | 0.03 units on a scale | Standard Deviation 0.1 |
| Nelfilcon A | Ocular Health - Biomicroscopy | Limbal Hyperemia (Temporal) | 0.44 units on a scale | Standard Deviation 0.4 |
| Nelfilcon A | Ocular Health - Biomicroscopy | Corneal Staining Extent (Inferior) | 0.41 units on a scale | Standard Deviation 0.7 |
| Nelfilcon A | Ocular Health - Biomicroscopy | Corneal Staining Extent (Temporal) | 0.09 units on a scale | Standard Deviation 0.3 |
| Nelfilcon A | Ocular Health - Biomicroscopy | Conjunctival Staining (Inferior) | 0.19 units on a scale | Standard Deviation 0.4 |
| Nelfilcon A | Ocular Health - Biomicroscopy | Corneal Staining Extent (Superior) | 0.22 units on a scale | Standard Deviation 0.4 |
| Nelfilcon A | Ocular Health - Biomicroscopy | Bulbar Hyperemia (Inferior) | 0.72 units on a scale | Standard Deviation 0.4 |
| Nelfilcon A | Ocular Health - Biomicroscopy | Conjunctival Indent (Superior) | 0.06 units on a scale | Standard Deviation 0.3 |
| Nelfilcon A | Ocular Health - Biomicroscopy | Conjunctival Staining (Superior) | 0.13 units on a scale | Standard Deviation 0.3 |
| Nelfilcon A | Ocular Health - Biomicroscopy | Limbal Hyperemia (Nasal) | 0.53 units on a scale | Standard Deviation 0.5 |
| Nelfilcon A | Ocular Health - Biomicroscopy | Limbal Hyperemia (Inferior) | 0.41 units on a scale | Standard Deviation 0.5 |
| Nelfilcon A | Ocular Health - Biomicroscopy | Bulbar Hyperemia (Nasal) | 0.88 units on a scale | Standard Deviation 0.2 |
| Nelfilcon A | Ocular Health - Biomicroscopy | Conjunctival Staining (Temporal) | 0.28 units on a scale | Standard Deviation 0.5 |
| Nelfilcon A | Ocular Health - Biomicroscopy | Corneal Staining Type (Central) | 0.00 units on a scale | Standard Deviation 0 |
| Nelfilcon A | Ocular Health - Biomicroscopy | Conjunctival Indent (Inferior) | 0.06 units on a scale | Standard Deviation 0.3 |
| Nelfilcon A | Ocular Health - Biomicroscopy | Conjunctival Staining (Nasal) | 0.34 units on a scale | Standard Deviation 0.6 |
| Nelfilcon A | Ocular Health - Biomicroscopy | Corneal Staining Type (Nasal) | 0.19 units on a scale | Standard Deviation 0.8 |
| Nelfilcon A | Ocular Health - Biomicroscopy | Conjunctival Indent (Temporal) | 0.00 units on a scale | Standard Deviation 0 |
| Nelfilcon A | Ocular Health - Biomicroscopy | Corneal Staining Depth (Inferior) | 0.25 units on a scale | Standard Deviation 0.5 |
| Nelfilcon A | Ocular Health - Biomicroscopy | Corneal Staining Type (Temporal) | 0.16 units on a scale | Standard Deviation 0.4 |
| Etafilcon A | Ocular Health - Biomicroscopy | Conjunctival Staining (Nasal) | 1.29 units on a scale | Standard Deviation 1.2 |
| Etafilcon A | Ocular Health - Biomicroscopy | Limbal Hyperemia (Temporal) | 0.89 units on a scale | Standard Deviation 0.7 |
| Etafilcon A | Ocular Health - Biomicroscopy | Limbal Hyperemia (Superior) | 0.68 units on a scale | Standard Deviation 0.7 |
| Etafilcon A | Ocular Health - Biomicroscopy | Bulbar Hyperemia (Nasal) | 0.96 units on a scale | Standard Deviation 0.3 |
| Etafilcon A | Ocular Health - Biomicroscopy | Bulbar Hyperemia (Temporal) | 0.96 units on a scale | Standard Deviation 0.2 |
| Etafilcon A | Ocular Health - Biomicroscopy | Bulbar Hyperemia (Superior) | 0.64 units on a scale | Standard Deviation 0.5 |
| Etafilcon A | Ocular Health - Biomicroscopy | Bulbar Hyperemia (Inferior) | 0.64 units on a scale | Standard Deviation 0.5 |
| Etafilcon A | Ocular Health - Biomicroscopy | Limbal Hyperemia (Nasal) | 0.96 units on a scale | Standard Deviation 0.7 |
| Etafilcon A | Ocular Health - Biomicroscopy | Limbal Hyperemia (Inferior) | 0.75 units on a scale | Standard Deviation 0.8 |
| Etafilcon A | Ocular Health - Biomicroscopy | Corneal Staining Type (Central) | 0.18 units on a scale | Standard Deviation 0.5 |
| Etafilcon A | Ocular Health - Biomicroscopy | Corneal Staining Type (Nasal) | 0.14 units on a scale | Standard Deviation 0.5 |
| Etafilcon A | Ocular Health - Biomicroscopy | Corneal Staining Type (Temporal) | 0.25 units on a scale | Standard Deviation 0.7 |
| Etafilcon A | Ocular Health - Biomicroscopy | Corneal Staining Type (Superior) | 0.07 units on a scale | Standard Deviation 0.3 |
| Etafilcon A | Ocular Health - Biomicroscopy | Corneal Staining Type (Inferior) | 0.50 units on a scale | Standard Deviation 0.9 |
| Etafilcon A | Ocular Health - Biomicroscopy | Corneal Staining Extent (Central) | 0.07 units on a scale | Standard Deviation 0.2 |
| Etafilcon A | Ocular Health - Biomicroscopy | Corneal Staining Extent (Nasal) | 0.04 units on a scale | Standard Deviation 0.1 |
| Etafilcon A | Ocular Health - Biomicroscopy | Corneal Staining Extent (Temporal) | 0.11 units on a scale | Standard Deviation 0.3 |
| Etafilcon A | Ocular Health - Biomicroscopy | Corneal Staining Extent (Superior) | 0.04 units on a scale | Standard Deviation 0.1 |
| Etafilcon A | Ocular Health - Biomicroscopy | Corneal Staining Extent (Inferior) | 0.32 units on a scale | Standard Deviation 0.6 |
| Etafilcon A | Ocular Health - Biomicroscopy | Corneal Staining Depth (Central) | 0.14 units on a scale | Standard Deviation 0.4 |
| Etafilcon A | Ocular Health - Biomicroscopy | Corneal Staining Depth (Nasal) | 0.07 units on a scale | Standard Deviation 0.3 |
| Etafilcon A | Ocular Health - Biomicroscopy | Corneal Staining Depth (Temporal) | 0.14 units on a scale | Standard Deviation 0.4 |
| Etafilcon A | Ocular Health - Biomicroscopy | Corneal Staining Depth (Superior) | 0.07 units on a scale | Standard Deviation 0.3 |
| Etafilcon A | Ocular Health - Biomicroscopy | Corneal Staining Depth (Inferior) | 0.29 units on a scale | Standard Deviation 0.5 |
| Etafilcon A | Ocular Health - Biomicroscopy | Conjunctival Staining (Temporal) | 0.68 units on a scale | Standard Deviation 0.9 |
| Etafilcon A | Ocular Health - Biomicroscopy | Conjunctival Staining (Superior) | 0.04 units on a scale | Standard Deviation 0.1 |
| Etafilcon A | Ocular Health - Biomicroscopy | Conjunctival Staining (Inferior) | 0.64 units on a scale | Standard Deviation 0.9 |
| Etafilcon A | Ocular Health - Biomicroscopy | Conjunctival Indent (Nasal) | 0.00 units on a scale | Standard Deviation 0 |
| Etafilcon A | Ocular Health - Biomicroscopy | Conjunctival Indent (Temporal) | 0.00 units on a scale | Standard Deviation 0 |
| Etafilcon A | Ocular Health - Biomicroscopy | Conjunctival Indent (Superior) | 0.00 units on a scale | Standard Deviation 0 |
| Etafilcon A | Ocular Health - Biomicroscopy | Conjunctival Indent (Inferior) | 0.00 units on a scale | Standard Deviation 0 |
| Filcon II 3 | Ocular Health - Biomicroscopy | Corneal Staining Depth (Temporal) | 0.17 units on a scale | Standard Deviation 0.4 |
| Filcon II 3 | Ocular Health - Biomicroscopy | Corneal Staining Type (Temporal) | 0.32 units on a scale | Standard Deviation 0.8 |
| Filcon II 3 | Ocular Health - Biomicroscopy | Bulbar Hyperemia (Nasal) | 0.95 units on a scale | Standard Deviation 0.4 |
| Filcon II 3 | Ocular Health - Biomicroscopy | Corneal Staining Depth (Superior) | 0.20 units on a scale | Standard Deviation 0.4 |
| Filcon II 3 | Ocular Health - Biomicroscopy | Corneal Staining Type (Nasal) | 0.07 units on a scale | Standard Deviation 0.4 |
| Filcon II 3 | Ocular Health - Biomicroscopy | Limbal Hyperemia (Temporal) | 0.38 units on a scale | Standard Deviation 0.5 |
| Filcon II 3 | Ocular Health - Biomicroscopy | Corneal Staining Depth (Inferior) | 0.40 units on a scale | Standard Deviation 0.5 |
| Filcon II 3 | Ocular Health - Biomicroscopy | Corneal Staining Type (Central) | 0.17 units on a scale | Standard Deviation 0.6 |
| Filcon II 3 | Ocular Health - Biomicroscopy | Limbal Hyperemia (Nasal) | 0.47 units on a scale | Standard Deviation 0.6 |
| Filcon II 3 | Ocular Health - Biomicroscopy | Conjunctival Staining (Nasal) | 1.65 units on a scale | Standard Deviation 0.9 |
| Filcon II 3 | Ocular Health - Biomicroscopy | Limbal Hyperemia (Inferior) | 0.33 units on a scale | Standard Deviation 0.5 |
| Filcon II 3 | Ocular Health - Biomicroscopy | Conjunctival Indent (Temporal) | 0.28 units on a scale | Standard Deviation 0.5 |
| Filcon II 3 | Ocular Health - Biomicroscopy | Conjunctival Staining (Temporal) | 1.65 units on a scale | Standard Deviation 0.9 |
| Filcon II 3 | Ocular Health - Biomicroscopy | Bulbar Hyperemia (Inferior) | 0.75 units on a scale | Standard Deviation 0.5 |
| Filcon II 3 | Ocular Health - Biomicroscopy | Limbal Hyperemia (Superior) | 0.30 units on a scale | Standard Deviation 0.4 |
| Filcon II 3 | Ocular Health - Biomicroscopy | Conjunctival Staining (Superior) | 1.48 units on a scale | Standard Deviation 0.8 |
| Filcon II 3 | Ocular Health - Biomicroscopy | Bulbar Hyperemia (Superior) | 0.72 units on a scale | Standard Deviation 0.5 |
| Filcon II 3 | Ocular Health - Biomicroscopy | Corneal Staining Extent (Temporal) | 0.10 units on a scale | Standard Deviation 0.2 |
| Filcon II 3 | Ocular Health - Biomicroscopy | Conjunctival Indent (Inferior) | 0.20 units on a scale | Standard Deviation 0.5 |
| Filcon II 3 | Ocular Health - Biomicroscopy | Corneal Staining Extent (Superior) | 0.22 units on a scale | Standard Deviation 0.5 |
| Filcon II 3 | Ocular Health - Biomicroscopy | Corneal Staining Extent (Nasal) | 0.02 units on a scale | Standard Deviation 0.1 |
| Filcon II 3 | Ocular Health - Biomicroscopy | Conjunctival Staining (Inferior) | 1.55 units on a scale | Standard Deviation 0.8 |
| Filcon II 3 | Ocular Health - Biomicroscopy | Corneal Staining Extent (Inferior) | 0.38 units on a scale | Standard Deviation 0.6 |
| Filcon II 3 | Ocular Health - Biomicroscopy | Corneal Staining Extent (Central) | 0.08 units on a scale | Standard Deviation 0.3 |
| Filcon II 3 | Ocular Health - Biomicroscopy | Bulbar Hyperemia (Temporal) | 0.98 units on a scale | Standard Deviation 0.4 |
| Filcon II 3 | Ocular Health - Biomicroscopy | Corneal Staining Depth (Central) | 0.10 units on a scale | Standard Deviation 0.3 |
| Filcon II 3 | Ocular Health - Biomicroscopy | Corneal Staining Type (Inferior) | 0.67 units on a scale | Standard Deviation 0.9 |
| Filcon II 3 | Ocular Health - Biomicroscopy | Conjunctival Indent (Superior) | 0.22 units on a scale | Standard Deviation 0.5 |
| Filcon II 3 | Ocular Health - Biomicroscopy | Corneal Staining Depth (Nasal) | 0.03 units on a scale | Standard Deviation 0.2 |
| Filcon II 3 | Ocular Health - Biomicroscopy | Corneal Staining Type (Superior) | 0.38 units on a scale | Standard Deviation 0.8 |
| Filcon II 3 | Ocular Health - Biomicroscopy | Conjunctival Indent (Nasal) | 0.28 units on a scale | Standard Deviation 0.5 |
Secondary
Overall Satisfaction
Participant's subjective response for overall satisfaction. Measured after 3 days of daily disposable lens wear. (4 point Likert Scale; Completely Satisfied, Somewhat Satisfied, Somewhat Dissatisfied, Completely Dissatisfied.
Time frame: 3 Days Follow-up
Population: Subjects were randomized to wear one or the other of the conventional hydrogel lenses; all subjects wore the Clariti silicone hydrogel lenses.
| Arm | Measure | Group | Value (NUMBER) |
|---|---|---|---|
| Nelfilcon A | Overall Satisfaction | Somewhat Satisfied | 8 participants |
| Nelfilcon A | Overall Satisfaction | Completely Satisfied | 7 participants |
| Nelfilcon A | Overall Satisfaction | Somewhat Dissatisfied | 1 participants |
| Nelfilcon A | Overall Satisfaction | Completely Dissatisfied | 0 participants |
| Etafilcon A | Overall Satisfaction | Completely Dissatisfied | 0 participants |
| Etafilcon A | Overall Satisfaction | Somewhat Dissatisfied | 1 participants |
| Etafilcon A | Overall Satisfaction | Completely Satisfied | 4 participants |
| Etafilcon A | Overall Satisfaction | Somewhat Satisfied | 9 participants |
| Filcon II 3 | Overall Satisfaction | Completely Satisfied | 15 participants |
| Filcon II 3 | Overall Satisfaction | Completely Dissatisfied | 1 participants |
| Filcon II 3 | Overall Satisfaction | Somewhat Dissatisfied | 3 participants |
| Filcon II 3 | Overall Satisfaction | Somewhat Satisfied | 11 participants |
Secondary
Overall Satisfaction, Comfort
Participant's subjective response for overall comfort satisfaction. Measured after 3 days daily disposable wear of lenses. (4 point Likert Scale; Completely Satisfied, Somewhat Satisfied, Somewhat Dissatisfied, Completely Dissatisfied.
Time frame: 3 Days Follow-up
Population: Subjects were randomized to wear one or the other of the conventional hydrogel lenses; all subjects wore the Clariti silicone hydrogel lenses.
| Arm | Measure | Group | Value (NUMBER) |
|---|---|---|---|
| Nelfilcon A | Overall Satisfaction, Comfort | Completely Dissatisfied | 0 participants |
| Nelfilcon A | Overall Satisfaction, Comfort | Somewhat Dissatisfied | 3 participants |
| Nelfilcon A | Overall Satisfaction, Comfort | Somewhat Satisfied | 5 participants |
| Nelfilcon A | Overall Satisfaction, Comfort | Completely Satisfied | 8 participants |
| Etafilcon A | Overall Satisfaction, Comfort | Completely Satisfied | 5 participants |
| Etafilcon A | Overall Satisfaction, Comfort | Completely Dissatisfied | 0 participants |
| Etafilcon A | Overall Satisfaction, Comfort | Somewhat Satisfied | 8 participants |
| Etafilcon A | Overall Satisfaction, Comfort | Somewhat Dissatisfied | 1 participants |
| Filcon II 3 | Overall Satisfaction, Comfort | Completely Satisfied | 16 participants |
| Filcon II 3 | Overall Satisfaction, Comfort | Somewhat Dissatisfied | 5 participants |
| Filcon II 3 | Overall Satisfaction, Comfort | Somewhat Satisfied | 9 participants |
| Filcon II 3 | Overall Satisfaction, Comfort | Completely Dissatisfied | 0 participants |
Secondary
Overall Satisfaction, Dryness
Participant's subjective response for overall dryness satisfaction. Measured after 3 days daily disposable wear of lenses. (4 point Likert Scale; Completely Satisfied, Somewhat Satisfied, Somewhat Dissatisfied, Completely Dissatisfied.
Time frame: 3 Days Follow-up
Population: Subjects were randomized to wear one or the other of the conventional hydrogel lenses; all subjects wore the Clariti silicone hydrogel lenses.
| Arm | Measure | Group | Value (NUMBER) |
|---|---|---|---|
| Nelfilcon A | Overall Satisfaction, Dryness | Completely Dissatisfied | 1 participants |
| Nelfilcon A | Overall Satisfaction, Dryness | Somewhat Dissatisfied | 4 participants |
| Nelfilcon A | Overall Satisfaction, Dryness | Somewhat Satisfied | 6 participants |
| Nelfilcon A | Overall Satisfaction, Dryness | Completely Satisfied | 5 participants |
| Etafilcon A | Overall Satisfaction, Dryness | Completely Satisfied | 6 participants |
| Etafilcon A | Overall Satisfaction, Dryness | Completely Dissatisfied | 0 participants |
| Etafilcon A | Overall Satisfaction, Dryness | Somewhat Satisfied | 5 participants |
| Etafilcon A | Overall Satisfaction, Dryness | Somewhat Dissatisfied | 3 participants |
| Filcon II 3 | Overall Satisfaction, Dryness | Completely Satisfied | 11 participants |
| Filcon II 3 | Overall Satisfaction, Dryness | Somewhat Dissatisfied | 5 participants |
| Filcon II 3 | Overall Satisfaction, Dryness | Somewhat Satisfied | 12 participants |
| Filcon II 3 | Overall Satisfaction, Dryness | Completely Dissatisfied | 2 participants |
Secondary
Overall Satisfaction, Handling
Participant's subjective response for overall handling satisfaction. Measured after 3 days of daily disposable lens wear. (4 point Likert Scale; Completely Satisfied, Somewhat Satisfied, Somewhat Dissatisfied, Completely Dissatisfied.
Time frame: 3 Days
Population: Subjects were randomized to wear one or the other of the conventional hydrogel lenses; all subjects wore the Clariti silicone hydrogel lenses.
| Arm | Measure | Group | Value (NUMBER) |
|---|---|---|---|
| Nelfilcon A | Overall Satisfaction, Handling | Completely Dissatisfied | 0 participants |
| Nelfilcon A | Overall Satisfaction, Handling | Somewhat Dissatisfied | 1 participants |
| Nelfilcon A | Overall Satisfaction, Handling | Somewhat Satisfied | 6 participants |
| Nelfilcon A | Overall Satisfaction, Handling | Completely Satisfied | 9 participants |
| Etafilcon A | Overall Satisfaction, Handling | Completely Satisfied | 7 participants |
| Etafilcon A | Overall Satisfaction, Handling | Completely Dissatisfied | 0 participants |
| Etafilcon A | Overall Satisfaction, Handling | Somewhat Satisfied | 3 participants |
| Etafilcon A | Overall Satisfaction, Handling | Somewhat Dissatisfied | 4 participants |
| Filcon II 3 | Overall Satisfaction, Handling | Completely Satisfied | 16 participants |
| Filcon II 3 | Overall Satisfaction, Handling | Somewhat Dissatisfied | 4 participants |
| Filcon II 3 | Overall Satisfaction, Handling | Somewhat Satisfied | 10 participants |
| Filcon II 3 | Overall Satisfaction, Handling | Completely Dissatisfied | 0 participants |
Secondary
Overall Satisfaction, Vision
Participant's subjective response for overall vision satisfaction. Measured after 3 days daily disposable wear of lenses. (4 point Likert Scale; Completely Satisfied, Somewhat Satisfied, Somewhat Dissatisfied, Completely Dissatisfied.
Time frame: 3 Days Follow-up
Population: Subjects were randomized to wear one or the other of the conventional hydrogel lenses; all subjects wore the Clariti silicone hydrogel lenses.
| Arm | Measure | Group | Value (NUMBER) |
|---|---|---|---|
| Nelfilcon A | Overall Satisfaction, Vision | Completely Dissatisfied | 0 participants |
| Nelfilcon A | Overall Satisfaction, Vision | Somewhat Dissatisfied | 0 participants |
| Nelfilcon A | Overall Satisfaction, Vision | Somewhat Satisfied | 2 participants |
| Nelfilcon A | Overall Satisfaction, Vision | Completely Satisfied | 14 participants |
| Etafilcon A | Overall Satisfaction, Vision | Completely Satisfied | 11 participants |
| Etafilcon A | Overall Satisfaction, Vision | Completely Dissatisfied | 0 participants |
| Etafilcon A | Overall Satisfaction, Vision | Somewhat Satisfied | 2 participants |
| Etafilcon A | Overall Satisfaction, Vision | Somewhat Dissatisfied | 1 participants |
| Filcon II 3 | Overall Satisfaction, Vision | Completely Satisfied | 24 participants |
| Filcon II 3 | Overall Satisfaction, Vision | Somewhat Dissatisfied | 0 participants |
| Filcon II 3 | Overall Satisfaction, Vision | Somewhat Satisfied | 6 participants |
| Filcon II 3 | Overall Satisfaction, Vision | Completely Dissatisfied | 0 participants |
Secondary
Subjective Response for Comfort
Participant's subjective response for comfort measured at baseline and 3 day follow-up. (Continuous Comfort Scale 0-100, 0=cannot be worn/causes pain, 100=cannot be felt ever)
Time frame: Baseline and 3 day follow-up
Population: Subjects were randomized to wear one or the other of the conventional hydrogel lenses; all subjects wore the Clariti silicone hydrogel lenses.
| Arm | Measure | Group | Value (MEAN) | Dispersion |
|---|---|---|---|---|
| Nelfilcon A | Subjective Response for Comfort | Baseline | 90.3 units on a scale | Standard Deviation 15.9 |
| Nelfilcon A | Subjective Response for Comfort | 3 day follow up | 84.5 units on a scale | Standard Deviation 12.2 |
| Etafilcon A | Subjective Response for Comfort | Baseline | 94.1 units on a scale | Standard Deviation 8.7 |
| Etafilcon A | Subjective Response for Comfort | 3 day follow up | 82.0 units on a scale | Standard Deviation 16.3 |
| Filcon II 3 | Subjective Response for Comfort | Baseline | 93.2 units on a scale | Standard Deviation 9.5 |
| Filcon II 3 | Subjective Response for Comfort | 3 day follow up | 81.5 units on a scale | Standard Deviation 20.1 |
Secondary
Subjective Response for Dryness
Participant's subjective response for dryness, measured at baseline and after 3 day follow-up of daily disposable wear of lenses. (Dryness Scale 0-100, 0=Cannot be worn/extremely dry, 100=no dryness experienced at any time).
Time frame: 3 Days Follow-up
Population: Subjects were randomized to wear one or the other of the conventional hydrogel lenses; all subjects wore the Clariti silicone hydrogel lenses.
| Arm | Measure | Value (MEAN) | Dispersion |
|---|---|---|---|
| Nelfilcon A | Subjective Response for Dryness | 80.6 units on a scale | Standard Deviation 16.8 |
| Etafilcon A | Subjective Response for Dryness | 81.6 units on a scale | Standard Deviation 19 |
| Filcon II 3 | Subjective Response for Dryness | 76.4 units on a scale | Standard Deviation 21.5 |
Secondary
Subjective Response for Handling (Insertion and Removal)
Participant's subjective response for handling (insertion and removal) measured at 3 day follow-up of daily disposable wear of lenses. (Handling Scale 0-100, 0=very hard to handle, 100=very easy to handle).
Time frame: 3 days follow-up
Population: Subjects were randomized to wear one or the other of the conventional hydrogel lenses; all subjects wore the Clariti silicone hydrogel lenses.
| Arm | Measure | Group | Value (MEAN) | Dispersion |
|---|---|---|---|---|
| Nelfilcon A | Subjective Response for Handling (Insertion and Removal) | Insertion | 92.9 units on a scale | Standard Deviation 11.6 |
| Nelfilcon A | Subjective Response for Handling (Insertion and Removal) | Removal | 88.6 units on a scale | Standard Deviation 14.8 |
| Etafilcon A | Subjective Response for Handling (Insertion and Removal) | Insertion | 74.1 units on a scale | Standard Deviation 23.6 |
| Etafilcon A | Subjective Response for Handling (Insertion and Removal) | Removal | 94.8 units on a scale | Standard Deviation 8 |
| Filcon II 3 | Subjective Response for Handling (Insertion and Removal) | Insertion | 91.3 units on a scale | Standard Deviation 10.1 |
| Filcon II 3 | Subjective Response for Handling (Insertion and Removal) | Removal | 93.9 units on a scale | Standard Deviation 11.8 |
Secondary
Subjective Response for Insertion
Participant's subjective response for insertion measured at baseline. (Insertion Handling Scale 0-100, 0=very hard to handle, 100=very easy to handle).
Time frame: Baseline
Population: Subjects were randomized to wear one or the other of the conventional hydrogel lenses; all subjects wore the Clariti silicone hydrogel lenses.
| Arm | Measure | Value (MEAN) | Dispersion |
|---|---|---|---|
| Nelfilcon A | Subjective Response for Insertion | 94.6 units on a scale | Standard Deviation 8.5 |
| Etafilcon A | Subjective Response for Insertion | 86.4 units on a scale | Standard Deviation 18.4 |
| Filcon II 3 | Subjective Response for Insertion | 91.0 units on a scale | Standard Deviation 15.1 |
Secondary
Subjective Response for Vision
Participant's subjective response for vision measured at baseline and at 3 day follow-up of daily disposable wear of lenses. (Vision Scale 0-100, 0=very blurry, 100=very clear).
Time frame: Baseline and 3 day follow-up
Population: Subjects were randomized to wear one or the other of the conventional hydrogel lenses; all subjects wore the Clariti silicone hydrogel lenses.
| Arm | Measure | Group | Value (MEAN) | Dispersion |
|---|---|---|---|---|
| Nelfilcon A | Subjective Response for Vision | Baseline | 93.8 units on a scale | Standard Deviation 8.2 |
| Nelfilcon A | Subjective Response for Vision | 3 day follow up | 94.8 units on a scale | Standard Deviation 5.4 |
| Etafilcon A | Subjective Response for Vision | Baseline | 93.0 units on a scale | Standard Deviation 9.6 |
| Etafilcon A | Subjective Response for Vision | 3 day follow up | 90.6 units on a scale | Standard Deviation 15.8 |
| Filcon II 3 | Subjective Response for Vision | Baseline | 94.1 units on a scale | Standard Deviation 6.1 |
| Filcon II 3 | Subjective Response for Vision | 3 day follow up | 95.2 units on a scale | Standard Deviation 5.1 |