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A Predictive Score Identifies Patients With Inadequate Bowel Preparation for Colonoscopy

A Predictive Score Identifies Patients With Inadequate Bowel Preparation for Colonoscopy

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT02093156
Enrollment
605
Registered
2014-03-20
Start date
2013-09-30
Completion date
2013-12-31
Last updated
2014-03-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bowel Preparation, Ottawa Score

Keywords

bowel preparation, Ottawa Score

Brief summary

Colonoscopy is the current standard method for evaluating the colorectal diseases. Adequate bowel preparation is essential for optimal visualization of the colorectal mucosa. However, inadequate bowel preparation (IBP) had been unexpectedly reported in up to 30% of patients undergoing colonoscopy. Many factors may influence the quality of bowel preparation, which can be broadly categorized as patient-related or procedure-related. It has been shown that split-dose regimen or some modified educational strategies can improve the quality of bowel preparation. For the patients with possible IBP before the performing of colonoscopy, it may be better to repeat bowel preparation with modified or enhanced strategies in case of failed intubation, missed lesions or unnecessarily increased cost. Thus, it is important to set up a model to predict the quality of bowel preparation individually.

Interventions

OTHERBowel preparation instructions

The same-day preparation method was used as previously reported. Briefly, all patients were instructed to have a regular diet for breakfast and lunch, but only clear liquids for dinner on the day before the colonoscopy. They were asked to drink two bags of PEG-ELP (polyethylene glycol electrolyte powder) dissolved in 2 L of water, or 45 mL of sodium phosphate be diluted in 240 mL of cool water follow with at least 1.5 L of water at 05:00-06:00 h within 2 h on the day of colonoscopy. Patients were encouraged to drink more clear liquids after purgatives for adequate hydration before colonoscopy.

Sponsors

Air Force Military Medical University, China
Lead SponsorOTHER

Study design

Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to 90 Years
Healthy volunteers
Yes

Inclusion criteria

* Patients aged 18-90 years old who undergoing colonoscopy

Exclusion criteria

* failed colonoscopy because of technical chanllenge or poor tolerance of patients * history of colorectal surgery * prior finding of severe colonic stricture or obstructing tumor * dysphagia * compromised swallowing reflex or mental status * significant gastroparesis or gastric outlet obstruction or ileum * known or suspected bowel obstruction or perforation * pregnancy * unable to give informed consent

Design outcomes

Primary

MeasureTime frameDescription
Adequate bowel preparation quality at the time of colonoscopy defined by Ottawa score<6up to 4 monthsOttawa score:A)cleanliness of each part of the colon: 0=excellent 1=good 2=fair 3=poor 4=inadequate B)fluid in whole colon: small=0 moderate=1 large=2 The bowel preparation was considered inadequate if (1) inadequate visualization on colonoscopy defined by Ottawa score≥6; (2) the colonoscopy was cancelled because of poor bowel preparation or personal reasons.

Secondary

MeasureTime frameDescription
Polyp detection rateup to 4 monthsThe proportion of participants with at least one polyp in each group

Countries

China

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026