Periodontitis
Conditions
Brief summary
Tooth loss in periodontitis patients is associated with patient and site factors as well as with treatment provided. Not much is known about long-term tooth loss in periodontitis patients in private practice in the UK. The study plans to follow-up 200 subjects with periodontitis (and currently on maintenance therapy) for 5 years. The effect of treatment provided, site and patient risk factors on tooth loss will be studied.
Interventions
None listed
Sponsors
University College, London
Study design
Observational model
CASE_ONLY
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
16 Years to 75 Years
Healthy volunteers
No
Inclusion criteria
1. Initial diagnosis of chronic or aggressive periodontitis (Lindhe et al. 1999, Lang et al. 1999), with at least two sites with PPD and CAL ≥5mm 2. Diagnosed and treated by the same periodontist (LN) 3. Willing to give written informed consent for study participation 4. Willing to undergo SPT as per standard of care for at least 5 years
Exclusion criteria
1. Serious medical history that prevents patients from undergoing dental treatment 2. History of rheumatic fever, heart murmur, mitral valve prolapse, artificial heart valve or other conditions requiring prophylactic antibiotic coverage prior to invasive dental procedures 3. Current alcohol or drug abuse 4. Self-reported pregnancy or lactation 5. Other severe acute or chronic medical or psychiatric condition or laboratory abnormality that may compromise trial participation and/or interpretation of trial results and, in the judgement of the investigator, would make the subject inappropriate for entry into this trial
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Tooth loss | 5 years |
Countries
United Kingdom
Outcome results
None listed