The Impact of Opioids in Fractures - a Case Control Study

Evaluation of Past Medications in Older Patients With Fractures and Patients Hospitalized for a Non-surgical Reason.

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02090972

Acronym

FROP

Enrollment

1000

Registered

2014-03-19

Start date

2014-03-31

Completion date

2015-02-28

Last updated

2016-03-31

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Fractures

Brief summary

In this study, the risk of opioid medications on fractures in older adults is investigated. Patients from the surgical department with fractures and control patients from the internal department of the same hospital are inquired with a standardized questionaire about demographic and clinical risk factors for fractures. Osteoporotic fracture risk is assessed using quantitative ultrasound. An impact of recent opioid medications on fractures is hypothesised.

Interventions

None listed

Study design

Observational model

CASE_CONTROL

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

60 Years to No maximum

Healthy volunteers

Inclusion criteria

for both groups: * age \> 60 years * written informed consent

Exclusion criteria

for both groups: * malignant Disease within the last 12 month * troubles with memory, dementia or Parkinsons disease * other fractures within the last 6 month

Design outcomes

Primary

Measure	Time frame	Description
Reported Opioid medication before hospital admission	interview: 20 min	Standardized assessment of opioid medications taken before fracture or hospital admission to evaluate the impact of opioids in fractures. Exact doses, substances and intake habits are inquired.

Secondary

Measure	Time frame	Description
Bone density measures using Quantitative ultrasound (SAHARA)	10 min	Evaluation of fracture risk due to reduced bone density is performed using quantitative ultrasound.

Countries

Germany

Outcome results