Renal Cancer
Conditions
Keywords
Questionnaire, DNA, saliva, kidney cancer, 13-218, high risk
Brief summary
This registry will help us develop better methods of: * Preventing these cancers * Diagnosing these cancers * Treating these cancers
Interventions
OTHERsalvia for germline DNA
BEHAVIORALthe Kidney Cancer Questionnaire
Patients will complete the appropriate surveys on either paper or on the computer/iPad in the office using REDCap software. If patients are unable to complete their questionnaires at the time of their in-office visit, a link to the questionnaires in REDCap will be emailed to them. The survey data that is collected in REDCap will be stored in REDCap. Clinic staff may also call patients to remind patients to complete questionnaires.
BEHAVIORALFamily History Questionnaire (when applicable)
Patients will complete the appropriate surveys on either paper or on the computer/iPad in the office using REDCap software. If patients are unable to complete their questionnaires at the time of their in-office visit, a link to the questionnaires in REDCap will be emailed to them. The survey data that is collected in REDCap will be stored in REDCap. Clinic staff may also call patients to remind patients to complete questionnaires.
OTHERBlood draw
BEHAVIORALEpidemiologic Questionnaire
Patients will complete the appropriate surveys on either paper or on the computer/iPad in the office using REDCap software. If patients are unable to complete their questionnaires at the time of their in-office visit, a link to the questionnaires in REDCap will be emailed to them. The survey data that is collected in REDCap will be stored in REDCap. Clinic staff may also call patients to remind patients to complete questionnaires.
Sponsors
Memorial Sloan Kettering Cancer Center
Study design
Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
Kidney Cancer Case Cohort: * Must be ≥ 18 years of age AND * Must be an English-speaker AND * Must have a diagnosis or suspicion of kidney cancer Family Member Cohort: * Must be ≥ 18 years of age AND * Must be an English-speaker AND * Must be a blood relative of the proband. Family members of probands including mother, father, sisters, brothers, half-sisters, half-brothers, daughters, sons, grandmothers, grandfathers, as well as aunts and uncles are eligible. These individuals need not have kidney cancer, as they will be used for segregation analysis of suspected variants found in the proband; requesting DNA from relatives is required. Control Cohort: * Must be ≥ 18 years of age AND * Must be an English-speaker AND * Must not have a personal history of cancer, with the exception of nonmelanoma skin cancer, AND * Must not be a blood relative of any cases or controls enrolled in this study
Exclusion criteria
* Patients who, in the opinion of the primary MSKCC clinician or the investigator, have a condition that precludes their ability to provide an informed consent
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| establish a kidney cancer registry | 5 years | with detailed epidemiologic data and germline DNA available for next generation sequencing from consenting patients, selected family members, and healthy unrelated controls. |
Countries
United States
Contacts
CONTACTJonathan Coleman, MD
CONTACTKenneth Offit, MD
PRINCIPAL_INVESTIGATORJonathan Jonathan, MD
Memorial Sloan Kettering Cancer Center
Outcome results
None listed