Urinary Tract Infections
Conditions
Keywords
Cranberry, Proanthocyanidins, Urinary catabolites
Brief summary
The purpose of this cross over pilot study is to investigate the urinary catabolites of Proanthocyanidines (PACs) as biomarkers of cranberry extracts in healthy young women.
Interventions
DIETARY_SUPPLEMENTCranberry extract
The aim of this pilot study is to evaluate the urinary catabolites of PACs as a biomarker of consumption of cranberry extracts within 9 hours of intercourse. Once a week, for 3 weeks, the women will receive a sequence of 3 different cranberry extracts (72 mg, 36 mg and 2mg (placebo)). The participant will have to collect its urine for a period of 9 hours in 3 different containers (one different container for 3 hours).
Sponsors
Laval University
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
BASIC_SCIENCE
Masking
QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
FEMALE
Age
18 Years to 40 Years
Healthy volunteers
Yes
Inclusion criteria
* Healthy women. * 18 to 40 years.
Exclusion criteria
* No internet access. * No refrigerator access during the 9 hours of sample collection. * Women who had or expect to take antibiotic. * Women who had or expect to take cranberries, blueberries or bilberries in the form of berries, juice or extracts. * Women who had or expect to take dark chocolate. * Women who had personal history of acute or chronic renal failure.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Urinary catabolites of PACs | within 9 hours following the intake of cranberry extracts |
Countries
Canada
Outcome results
None listed