FindTrial
Sign In

Effect of Low-calorie Diet on Serum Lipids, Adipokines, Insulin Resistance and Also Body Composition in Women With Metabolic Syndrome

Effect of Hypocaloric Diet on Biomarkers of Metabolic Profile, Insulin Resistance and Body Composition in Women With Metabolic Syndrome

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT02087709
Enrollment
30
Registered
2014-03-14
Start date
2008-05-31
Completion date
2010-02-28
Last updated
2014-03-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Weight Loss, Insulin Resistance, Adipokines

Brief summary

The purpose of this study is to evaluate the effect of a hypocaloric diet on biomarkers associated with insulin resistance, metabolic profile and body composition in women with Metabolic Syndrome.

Interventions

OTHERLow-calorie diet

Sponsors

Rio de Janeiro State University
CollaboratorOTHER
Conselho Nacional de Desenvolvimento Científico e Tecnológico
CollaboratorOTHER_GOV
Rio de Janeiro State Research Supporting Foundation (FAPERJ)
CollaboratorOTHER_GOV
Universidade Federal do Rio de Janeiro
Lead SponsorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
FEMALE
Age
30 Years to 45 Years
Healthy volunteers
No

Inclusion criteria

* BMI of 30-34.9 kg/m2, diagnostic of metabolic syndrome based on National Cholesterol Education Panel ATPIII (2002)

Exclusion criteria

* Diabetes mellitus, non-treated thyroid disease, treatment with lipid-lowering drugs and glucocorticoids or weight loss treatment within the previous 3 months.

Design outcomes

Primary

MeasureTime frameDescription
WeightChange from baseline at 3rd monthChange from baseline weight (Kg) at 3rd month.

Secondary

MeasureTime frameDescription
Insulin resistance markersChange from baseline at 3rd monthChange from baseline fasting glucose and insulin, homeostasis model assessment-insulin resistance and quantitative insulin sensitivity check index at 3rd month, samples were stored at -20 degrees.

Other

MeasureTime frameDescription
AdipokinesChange from baseline at 3rd monthThe change from baseline leptin and adiponectin at 3rd month, samples were stored at -20 degrees

Countries

Brazil

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026