Hip Osteoarthritis
Conditions
Brief summary
The objective of this study is to assess the changes in daily physical activity and gait pattern, following a viscosupplement injection among a population who is suffering from hip osteoarthritis. A kinetic and kinematic gait analysis, an Actigraph activity monitor, a functional Timed-Stair-Test and two questionnaires (Medical Outcome Study Short-Form36 (MOS-SF36), Hip disability and Osteoarthritis Outcome Score (HOOS)) about how the pathology affects the quality of life, will be use.
Interventions
DRUGHyaluronan
Intra-articular injection
DRUGBupivacaine
Extra-capsular injection
Sponsors
Laval University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
TRIPLE (Subject, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
45 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
* From 45 years old to 65 years old * Clinically symptomatic moderate or severe hip osteoarthritis (Tönnis Grade II to III) * Capacity to keep steady upright position and walking during 15 minutes * Body mass index \< 40kg/m2
Exclusion criteria
* Bilateral hip osteoarthritis * No broken hip or leg during the last 12 months * Bone necrosis * Rheumatoid arthritis, articular chondrocalcinosis, metabolic bone disease, psoriasis, gout, active infection * Per os corticosteroid treatment * Corticosteroid injection \< 3 months * Viscosupplement injection \< 6 months * Hypersensitivity to hyaluronic acid products * Planed surgery during study duration * Physical or mental disability to fill in questionnaires and/or to participate to follow-up
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change in hip flexion-extension range of motion | Change from Baseline at 6 months | Subtraction between maximum and minimum flexion measured with motion capture system during gait |
| Change in daily physical activity | Change from Baseline at 6 months | Intensity and duration of the daily physical activity measured with pedometer |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Change in hip pain | change from Baseline at 6 months | Questionnaires HOOS |
| Change in quality of life | Change from Baseline at 6 months | Questionnaires: MOS-SF36 and HOOS |
| Change in walking cadence | Change from Baseline at 6 months | Measured during 3D gait analysis |
Countries
Canada
Outcome results
None listed