Skip to content

The Influence of Lidocaine Volume on Discomfort During Administration of Local Anesthetic

The Influence of Lidocaine Volume on Discomfort During Administration of Local Anesthetic

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT02086292
Enrollment
36
Registered
2014-03-13
Start date
2014-02-28
Completion date
2014-06-30
Last updated
2016-09-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Needlestick Injuries

Keywords

Injections, Lidocaine, Pain, Healthy volunteers

Brief summary

The aim of the study is to find a simple method for pain reduction that can be used in clinical practice when administering digital nerve block with a single subcutaneous injection. It will be investigated whether a smaller volume of lidocaine can decrease pain during injection.

Detailed description

Healthy volunteers will receive a single subcutaneous injection digital nerve block at the base of each ring finger. 2ml 1% lidocaine in one of the fingers, and 1 ml 2% lidocaine in the other. After each injection, the subject will be asked to evaluate the pain on a visual analog scale (0-100 mm). Additionally the sensibility will be tested with a Semmes-Weinstein monofilament, to evaluate if the different methods achieve desired anesthetic effect.

Interventions

PROCEDURE2 ml 1% Lidocaine
PROCEDURE1 ml 2% Lidocaine

Sponsors

St. Olavs Hospital
CollaboratorOTHER
Norwegian University of Science and Technology
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
TREATMENT
Masking
SINGLE (Subject)

Eligibility

Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
Yes

Inclusion criteria

* age 18 - 65

Exclusion criteria

* regular use of analgesics * known hypersensitivity of local anaesthetic * renal-, heart- or liver disease * known peripheral neuropathy or diabetes mellitus * local infection on injection site * circulation disorders in upper extremities (e.g. Raynaud´s phenomenon)

Design outcomes

Primary

MeasureTime frameDescription
pain60 seconds1. visual analog scale 0-100mm 2. questionnaire

Countries

Norway

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026