Changes of Dendritic Cells in Acute Lung Injury

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02083393

Enrollment

Registered

2014-03-11

Start date

2011-06-30

Completion date

2014-12-31

Last updated

2015-05-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Lung Injury

Keywords

dendritic cell

Brief summary

To observe changes of circulating and tissue dendritic cells in acute lung injury,including invasive aspergillosis pneumonia

Detailed description

Change of circulating and tissular dendritic cells of patients with acute lung injury was still unclear, we used a flow cytometry-based assay to quantify circulating and tissular DCs and their HLA-DR surface expression at the time of diagnosis and during the first week of evolution in patients with acute lung injury, and healthy people as controls.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 90 Years

Healthy volunteers

Yes

Inclusion criteria

* Sepsis induced acute lung injury

Exclusion criteria

* Younger than 18-year-old * Pregnancy * Cancer or organ transplant * Asthma * COPD * Heart Failure

Design outcomes

Primary

Measure	Time frame
28-day mortality	28day

Countries

China

Outcome results