Balanced Fluids, Plasmalyte, SIRS
Conditions
Keywords
hyperchloremic acidosis, balanced fluids, plasmalyte
Brief summary
This observational study evaluates the impact of high and low chloride containing IV fluids on administrative and clinical outcomes. The study uses a large electronic health dataset and examines patients receiving fluid replacement and resuscitation. The hypothesis is that high chloride solutions are associated with adverse outcomes as measured by administrative data and by clinical parameters.
Interventions
None listed
Sponsors
Baxter Healthcare Corporation
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Adults meeting SIRS criteria receiving at least 500 mL of fluid replacement on day of SIRS.
Exclusion criteria
* Receipt of starches or other colloids
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Mortality | Hospitalization, Expected Length of inpatient stay is approximately 7 days | Inpatient mortality. Expected Length of inpatient stay is approximately 7 days |
Secondary
| Measure | Time frame |
|---|---|
| Length of Stay | inpatient hospitalization, Expected Length of inpatient stay is approximately 7 days |
| Acute renal failure | inpatient hospitalization, Expected Length of inpatient stay is approximately 7 days |
| dysrhythmias | inpatient hospitalization, Expected Length of inpatient stay is approximately 7 days |
| Electrolyte disorders | inpatient hospitalizationExpected Length of inpatient stay is approximately 7 days |
| Infections | inpatient hospitalization, Expected Length of inpatient stay is approximately 7 days |
Other
| Measure | Time frame |
|---|---|
| readmission | 30, 60 and 90 day |
Countries
United States
Outcome results
None listed