Oral Glucose Tolerance Testing After Gestational Diabetes

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02082301

Enrollment

118

Registered

2014-03-10

Start date

2012-10-31

Completion date

2019-12-31

Last updated

2020-02-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gestational Diabetes, Obesity, Pregnancy

Brief summary

This is an observation study of women with gestational diabetes. Subjects recruited undergo immediate postpartum diabetic screening prior to discharge. Post-partum screening for overt diabetes is repeated 6-12 weeks postpartum. The outcome of interest is the utility of an immediate post partum screen for overt diabetes compared to a traditional 6 week test.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

FEMALE

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Singleton pregnancy * Gestational diabetes

Exclusion criteria

* Multiple gestations * pre-pregnancy diabetes

Design outcomes

Primary

Measure	Time frame	Description
Primary outcome: sensitivity of immediate post partum screen	Immediate post partum	2 hour fasting 75g OGTT immediately post partum. This is compared to a traditional 6 week post partum 75g OGTT for the sensitivity, positive and negative predictive value of the immediate post partum test

Secondary

Measure	Time frame	Description
Secondary outcome: physiology	3 time points: antepatum, immediate postpartum, 6 weeks post partum	A small sub-cohort of women will undergo an additional 2 hour fasting 75g OGTT in the third trimester with measurements of insulin, cytokines, lipids.

Countries

United States

Outcome results