Patients Who Underwent Surgery for Congenital Heart Disease
Conditions
Keywords
tidal volume, congenital heart disease, mortality
Brief summary
High tidal volume during mechanical ventilation has been reported to increase mortality in patients with acute lung injury or acute respiratory distress syndrome. High tidal volume was also reported to be associated with increased mortality in adult patients without acute lung injury or acute respiratory distress syndrome. However, the influence of high tidal volume on clinical outcome in pediatric patients who underwent surgery for congenital heart disease has not been evaluated yet. The investigators attempted to evaluate the effect of tidal volume on clinical outcome in both cyanotic and non-cyanotic congenital heart disease.
Detailed description
High tidal volume during mechanical ventilation has been reported to increase mortality in patients with acute lung injury or acute respiratory distress syndrome. High tidal volume was also reported to be associated with increased mortality in adult patients without acute lung injury or acute respiratory distress syndrome. However, the influence of high tidal volume on clinical outcome in pediatric patients who underwent surgery for congenital heart disease has not been evaluated yet. The investigators attempted to evaluate the effect of tidal volume on clinical outcome in both cyanotic and non-cyanotic congenital heart disease.
Interventions
PROCEDURESurgery for congenital heart disease
Sponsors
Samsung Medical Center
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
No minimum to 10 Years
Healthy volunteers
No
Inclusion criteria
* pediatric patients who underwent surgery for congenital heart disease with cardiopulmonary bypass between 2009 and 2013 in Samsung Medical Center
Exclusion criteria
* patients who lack data regarding mortality, creatinine, estimated glomerular filtration rate, or urine output.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Patient Mortality | six month after surgery | Patient Mortality at six month after surgery |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Patient Mortality | in-hospital, one-month, and one-year after surgery | In-hospital, one-month and one-year mortality after surgery |
| acute kidney injury as defined by RIFLE criteria (for Risk, Injury, Failure, Loss, End-stage kidney disease) | during one week after surgery | acute kidney injury as defined by RIFLE criteria (for Risk, Injury, Failure, Loss, End-stage kidney disease) |
Countries
South Korea
Outcome results
None listed