Stroke
Conditions
Keywords
stroke, deglutition disorders, cough, aspiration pneumonia, diaphragm, respiratory function
Brief summary
To assess coughing force during reflex coughing test in those with severe dysphagia and severe aspiration and compare them to than those with stroke patients with no signs of dysphagia/aspiration.
Detailed description
Severe aspiration with a compromised cough function can be a risk factor of aspiration pneumonia. Reflexive coughing can be tested by administration of citric acid via a nebulizer. The objective of this study is to measure the cough force produced via citric acid inhalation challenge, and determine if those with severe aspiration with severe dysphagia have more weak cough force during reflexive cough testing that those post-stroke patients with no signs of aspiration or dysphagia after stroke. We also aimed to measure the strenght of the respiratory measures with the use of surface EMG.
Interventions
None listed
Sponsors
The Catholic University of Korea
Study design
Observational model
COHORT
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
Yes
Inclusion criteria
* Confirmed stroke lesions * Confirmed aspiration during vfss or fees examinations
Exclusion criteria
* Episode of acute pneumonia or pulmonary embolism at time of enrollment * Previous history of chronic respiratory disorders or other systemic disorders that may affect respiratory function ( ex, rheumatoid disease, spinal cord injury) * Stroke patients with multiple brain lesions * Episode of Diaphragm weakness due to peripheral polyneuropathy or unilateral phrenic nerve palsy * Previous episode of abdominal or thoracic surgery within one year of enrollment * Concomitant diagnosis of myopathy, muscular dystrophy or other disorders that may affect respiratory muscles. * Episode of rib fracture within one year of enrollment * Chronic alcoholism * Patient with previous diagnosis of dementia or with impaired cognitive function that may limit full participation at the evaluation * Patient with tracheostomy state
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Coughing force | baseline one time | Coughing force as assessed by reflexive cough test |
Secondary
| Measure | Time frame |
|---|---|
| Coughing force during voluntary coughing | baseline one time |
Other
| Measure | Time frame |
|---|---|
| Spirometry findings (Forced vital capacity, forced expiratory volume at one second) | baseline one time |
| Maximal inspiratory and expiratory pressure | baseline one time |
| Root mean square values of respiratory muscles | baseline one time |
| Diaphragm excursion as assessed by M mode sonography | baseline one time |
Countries
South Korea
Outcome results
None listed