Intra Ocular Pressure
Conditions
Keywords
Cannabis, Intra ocular pressure, Ocular perfusion, Blood pressure
Brief summary
Purpose of study: to check the effect of medical cannabis given for approved medical indications on ocular parameters including intra ocular pressure, optic nerve fibers thickness and choroidal thickness.
Detailed description
Purpose of study: to check the effect of medical cannabis given for approved medical indications on ocular parameters including intra ocular pressure, Retinal Nerve Fiber Layer (RNFL) thickness, optic nerve fibers thickness and choroidal thickness. Adult patients with no ocular pathology that are being treated in the neurology or pain clinics with medical cannabis for different indications, were examined in the eye clinic. First examination took place after the patient was not smoking for 5 hours. Three more examinations took place 1 hour 3 hours and 5 hours after smoking cannabis. The following parameters were checked: blood pressure, pulse, visual acuity, intra ocular pressure, corneal thickness, axial length, slit lamp examination of anterior segment, fundoscopy and Optical Coherence Tomography (OCT) of the retina, and optic nerve.
Interventions
None listed
Sponsors
Carmel Medical Center
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 90 Years
Healthy volunteers
No
Inclusion criteria
* Age over 18 * Treated with medical cannabis for approved medical indications
Exclusion criteria
* Known ocular pathology * Topical or systemic treatment for intra ocular pressure * Previous topical, intra ocular or systemic steroid treatment
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Intra ocular pressure | 5 hours |
Countries
Israel
Contacts
Primary ContactOrna Geyer, MD
Outcome results
None listed