Hyaluronan in Embryo Transfer Media

Effect of Hyaluronan Enriched Embryo Transfer Media on IVF Outcome

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02077608

Enrollment

580

Registered

2014-03-04

Start date

2010-01-31

Completion date

2013-12-31

Last updated

2014-03-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infertility

Keywords

In vitro fertilization, Embryotransfer, Hyaluronan, Pregnancy rate, Implantation rate

Brief summary

Prospective randomized double blind comparison of hyaluronan enriched embryotransfer media and conventional embryotransfer media in human IVF treatments. Embryos selected for transfer are incubated in a culture media containing high concentration of hyaluronan or low concentration of hyaluronan. Primary outcome: implantation and pregnancy rates

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

FEMALE

Age

18 Years to 48 Years

Healthy volunteers

Inclusion criteria

* Infertile patients * entering in vitro fertilization treatment * at least 1 embryo transferred

Exclusion criteria

* IVF treatment with donated oocytes * No embryo available for transfer

Design outcomes

Primary

Measure	Time frame	Description
Clinical pregnancy rate	5 weeks after embryo transfer	Number of clinical pregnancies (gestational sacs visible by ultrasound examination) divided by the number of embryotransfers
Implantation rate	5 weeks after embryotransfer	Number of embryos implanted (No. of gestational sacs) divided by the number of embryos implanted

Secondary

Measure	Time frame	Description
Multiple pregnancy rate	5 weeks after embryotransfer	Number of multiple pregnancies divided by the number of embryotransfers
Delivery rate	40 weeks after embryo transfer	Number of delivery divided by the number of embryo transfers

Countries

Hungary

Outcome results