Transcutaneous Electrical Nerve Stimulation
Conditions
Keywords
transcutaneous electrical nerve stimulation, transcranial magnetic stimulation
Brief summary
Recently, non-invasive brain stimulation has become a powerful tool in both basic research and clinical application. Among several non-invasive brain stimulation techniques, transcranial magnetic stimulation (TMS) and transcranial direct current stimulation (tDCS) have received the most attention. About DC stimulation, the change of polarity could modulate the spontaneous neuronal activity and make effect on decision making, language, memory, sensory perception, and pain. In spite of that the concept of transcranial alternating current stimulation (tACS) is not novel, AC is relatively safe compared to DC, and researches have revealed that AC might potentially have the effect on the cortical excitability. However, there are still many areas about AC stimulation which remain unknown, such as mechanism, application, and potential influence on cortical excitability.
Interventions
DEVICEtranscutaneous electrical nerve stimulation, TENS
Then participants will receive stimulation for 20 minutes.
Sponsors
Chang Gung University
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
TREATMENT
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Age
20 Years to 65 Years
Healthy volunteers
Yes
Inclusion criteria
* Healthy adults
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Motor evoked potential | Baseline | measure of intracortical inhibition on abductor pollicis brevis by single-pulse TMS. |
| Intracortical inhibition, ICI | Baseline,2 hours, 2.5 hours,and 3 hours | Measure of changes in intracortical inhibition on abductor pollicis brevis by paired-pulse TMS. |
| intracortical facilitation, ICF | Baseline,Baseline,2 hours, 2.5 hours,and 3 hours | Measure of changes in intracortical inhibition on abductor pollicis brevis by paired-pulse TMS. |
Countries
Taiwan
Outcome results
None listed