Metabolic Syndrome
Conditions
Keywords
Patients with metabolic syndrome age between 30 to 64: Central obesity (Men ≥ 90 cm Women ≥ 85 cm), Plasma triglycerides ≥ 150 mg/dL, HDL cholesterol Men < 40 mg/dL, Women < 50 mg/dL, Blood pressure ≥130/85 mm Hg (or treatment for hypertension),, Fasting plasma glucose ≥ 100 mg/dL
Brief summary
Patients with metabolic syndrome living in Seoul area are included in this prospective registry for more than 10 years. All enrolled patients undergo thorough medical history survey. Enrolled patients will have coronary CT, 2D echocardiogram, treadmill test, pulse wave velocity, augmentation index, carotid intima-media thickness, and abdominal fat mass evaluation. Moreover, lipid profiles and inflammatory markers such as hsCRP, IL-6, TNF-alpha, VCAM-1, ICAM-1, adiponectin, MMP-9 will be measured. All participants will repeat the test and survey every year in Korea University Hospital.
Interventions
None listed
Sponsors
Korea University Anam Hospital
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
30 Years to 64 Years
Healthy volunteers
Yes
Inclusion criteria
3 out of 5 criteria * Central obesity: Men ≥ 90 cm Women ≥ 85 cm * Plasma triglycerides ≥ 150 mg/dL * HDL cholesterol Men \< 40 mg/dL, Women \< 50 mg/dL * Blood pressure ≥130/85 mm Hg (or treatment for hypertension) * Fasting plasma glucose ≥ 100 mg/dL * Age between 30 to 64 * Consent to our registry protocol
Exclusion criteria
* Patients who could not undergo coronary CT, 2D echocardiogram, treadmill test, and pulse wave velocity.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Cardiovascular events | 10 years | Cardiovascular events such as fatal and non-fatal myocardial infarction, heart failure, need for coronary and peripheral revascularization, stroke, all-cause death, and cardiac death. |
Countries
South Korea
Outcome results
None listed