Prophylactic Antibiotic in Treatment of Fingertip Amputation

The Use of Prophylactic Antibiotic in Treatment of Fingertip Amputation: A Randomized Prospective Trial

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02077400

Enrollment

Registered

2014-03-04

Start date

2006-01-31

Completion date

2015-02-28

Last updated

2015-07-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infection Rate After Fingertip Amputation

Brief summary

Fingertip amputation is a common injury. Considerable controversy exists as to whether prophylactic antibiotics are necessary for this injury. The investigators goal was to compare the rate of infections among subgroups with and without prophylactic antibiotic treatment. The study hypothesis was that infection rates were similar in the two groups.

Interventions

DRUGCephazolin

Cephazolin

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

PREVENTION

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

* fingertip amputation with bone exposed

Exclusion criteria

* under the age of 18 years * if the patient had diabetes * oncological disorder * immune deficiency * bleeding disorder * used steroids regularly * presented with a grossly contaminated wound or other injury requiring antibiotic treatment * were currently taking antibiotics, or had a previous allergic reaction to cephalosporins.

Design outcomes

Primary

Measure	Time frame
infection rate	1 month

Countries

Israel

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026