Physical Conditioning, Human, Cognition
Conditions
Keywords
Aerobic exercise, Cognitive function, Executive function, Brain-derived neurotrophic factor
Brief summary
The present study will investigate the effects of aerobic exercise on cognition and growth factors including brain-derived neurotrophic factor (BDNF) in young adults aged 15-21 years. The included subjects will be randomized to three different groups including one control group and two exercise groups. Subjects randomized to the exercise groups will complete 30 minutes of aerobic exercise 3 times a week for 9 weeks incorporating low (group I) or high (group II) intensity aerobic exercise. The exercise will be conducted as running or indoor cycling (supervised). At baseline and 9-weeks follow-up all subjects will complete two cognitive tests (measures of concentration and sustained attention), a maximal cycling test (direct measures of VO2max), an intelligence quotient test, anthropometric measures, fasting blood samples and blood samples immediately following the cycling test. The blood samples will be analyzed for growth factors including BDNF and metabolic factors.
Interventions
BEHAVIORALLow intensity aerobic exercise
BEHAVIORALHigh intensity aerobic exercise
Sponsors
University of Southern Denmark
Study design
Allocation
RANDOMIZED
Intervention model
FACTORIAL
Primary purpose
SUPPORTIVE_CARE
Masking
SINGLE (Investigator)
Eligibility
Sex/Gender
ALL
Age
15 Years to 21 Years
Healthy volunteers
Yes
Inclusion criteria
* age 15-21
Exclusion criteria
* injury preventing one from being physically active
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The Flanker Task | 9 weeks |
| The AX-Continuous Performance test | 9 weeks |
| Brain-derived neurotrophic factor | 9 weeks |
Secondary
| Measure | Time frame |
|---|---|
| Intelligence quotient | 9 weeks |
Countries
Denmark
Outcome results
None listed