Changes in Cardiac Output
Conditions
Keywords
Cardiac output, Exhaled CO2, Nexfin, Esophageal Doppler
Brief summary
The investigators hypothesize that changes in blood circulation can be reflected by exhaled CO2 provided CO2-production in the tissues and ventilation from the lungs are stable. The investigators want to explore changes in cardiac output (the amount of blood being pumped out of the heart each minute) in patients using different devices: an esophagus ultrasound device measuring cardiac output, a finger cuff measuring blood pressure and cardiac output, and exhaled carbondioxide in the patients' breath measured by the ventilator. The investigators investigate patients after bypass surgery or heart valve replacement, and induce changes in cardiac output with passive leg raise or ventricular pacing.
Detailed description
Measurements with the finger cuff (pulse contour analyses) were aborted due to technical difficulties.
Interventions
OTHERVentricular pacing and passive leg raise
Ventricular pacing and passive leg raise
Sponsors
The Norwegian Air Ambulance Foundation
Oslo University Hospital
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
BASIC_SCIENCE
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 95 Years
Healthy volunteers
No
Inclusion criteria
* Persons 18 years or older scheduled to undergo arteriocoranary bypass surgery or aortic valve replacement.
Exclusion criteria
* Esophageal pathology, EF \<40%
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Changes in cardiac output | 5 Minutes |
Countries
Norway
Outcome results
None listed