Anemia, Renal Impairment, Thrombocytopenia
Conditions
Keywords
anemia, renal impairment, thrombocytopenia, anticoagulation, Coronary bypass, Aortic valve surgery, Mitral valve surgery, red blood cell, platelet, fresh frozen plasma, octaplas
Brief summary
Blood transfusion is a common procedure essential for the treatment of patients undergoing cardiac surgery. Inappropriate transfusions, however, not only incur needless healthcare costs, but increase unnecessary risks due to transfusion reactions and infectious and immunomodulative causes. Safe and appropriate patient care requires evaluated blood component prescription practices. Practically all patients undergoing cardiac surgery in Finland have a blood product booking from the Finnish Red Cross Blood Service. This registry contains large volumes of transfusion-related information on all Finnish patients undergoing cardiac surgery in Finnish centers. Participating hospitals were scattered to all geographical areas in Finland and concentrated to the most populated regions. Data on the blood product use, laboratory findings one month pre-operatively and 12 months post-operatively were available. Finnish hospitals have been required to provide information on hospital visits for the Finnish National Research and Development Centre for Welfare and Health for healthcare planning purposes. We used in part the original data sent by hospitals to the Finnish Hospital Discharge Register (FHDR).
Detailed description
Registry includes * \>21 000 patients who underwent coronary bypass, * \>4500 patients with aortic valve replacement, * \>4000 mitral valve operation.
Interventions
None listed
Sponsors
Study design
Eligibility
Inclusion criteria
* Cardiac surgery performed in Finnish University and Central hospitals * Blood product booking for surgery
Exclusion criteria
\-
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Octaplas | 12 months |
| Red blood cell infusions | 12 months |
| Platelet infusion | 12 months |
| Fresh frozen plasma | 12 months |
Secondary
| Measure | Time frame |
|---|---|
| All cause mortality | 12 months |
| myocardial infarction | 12 months |
| TIA/stroke/arterial embolism | 12 |
| re-operation due to bleeding | 12 months |