Antisocial Personality, Anxiety, Depression, Executive Dysfunction, Reading Disabilities, Substance Abuse
Conditions
Brief summary
The purpose of this study is to evaluate the effects of a computerized working memory training program on substance abuse, psychosocial functioning, cognitive performance and psychiatric problems in adults with substance abuse and attention problems.
Detailed description
The primary aim of this study is to examine the effects of 5 weeks of computerized working memory training on substance abuse. Secondary aims are to explore whether effects are mediated by changes in executive functions and/or moderated by personality. Also, effects on measures of psychosocial functioning, depression, anxiety and attention will be explored. Follow-up assessment will be conducted at 6 months post training.
Interventions
BEHAVIORALComputerized Cogmed working memory training
Computerized working memory training with Cogmed QM software. The QM software consists of a set of verbal and visual working memory tasks which is trained for 25-40 minutes each session.
BEHAVIORALTreatment as usual
Treatment as usual can consist of medication, psychotherapy, counseling, and psychological assessment.
Sponsors
Örebro Läns Landsting
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to 70 Years
Healthy volunteers
No
Inclusion criteria
* Treatment seeking adults with substance abuse and executive function deficits.
Exclusion criteria
* Acute intoxication or abstinence symptoms of any substance. * Psychosis.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change from baseline in substance abuse measured with Substance abuse scales in Adult Self Report (ASR; ASEBA). | Baseline and at 25 weeks |
Secondary
| Measure | Time frame |
|---|---|
| Change from baseline in Adult Self Report (ASR; ASEBA) Internalizing index. | Baseline and at 25 weeks |
| Change from baseline in Adult Self Report (ASR; ASEBA) Externalizing index. | Baseline and at 25 weeks |
| Change from baseline in Adult Self Report (ASR; ASEBA) Adaptive functioning scales. | Baseline and at 25 weeks |
| Change from baseline in Executive functioning measured with Behavior Rating Inventory of Executive Function-Adult (BRIEF-A). | Baseline and at 25 weeks |
| Change from baseline in Adult Self Report (ASR; ASEBA) Attention problems scale. | Baseline and at 25 weeks |
| Change from baseline in visual working memory measured with performance on Span board. | Baseline and at 25 weeks |
| Change from baseline in focused attention measured with performance on Conners Continuous Performance Test-II (CCPT-II). | Baseline and at 25 weeks |
| Change from baseline in vigilance measured with performance on Conners Continuous Performance Test-II (CCPT-II). | Baseline and at 25 weeks |
| Change from baseline in reading speed measured with performance on Reading speed in Diagnostic Reading and Writing Test (DLS; Swedish version). | Baseline and at 25 weeks |
| Change from baseline in verbal working memory measured with performance on Digit span. | Baseline and at 25 weeks |
Countries
Sweden
Contacts
Primary ContactRickard Ahlberg, doctoral student
Backup ContactKurt Skårberg, MD
Outcome results
None listed