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Injectable Lidocaine Versus Lidocaine/Tetracaine Patch for the Incision and Drainage of Skin Abscesses

Injectable Lidocaine Provides Similar Analgesia Compared to Transdermal Lidocaine/Tetracaine Patch for the Incision and Drainage of Skin Abscesses: A Randomized Controlled Trial

Status
Completed
Phases
Early Phase 1
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT02066818
Enrollment
20
Registered
2014-02-20
Start date
2008-01-31
Completion date
2010-01-31
Last updated
2014-02-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cutaneous Abscess, Pain

Keywords

local anesthetic, incision and drainage, pain, cutaneous abscess

Brief summary

Local anesthesia used for incision and drainage of abscesses is known to be painful. We studied the analgesia provided by a lidocaine/tetracaine patch compared to injectable lidocaine during incision and drainage (I&D) of skin abscesses. Local injection of lidocaine provided similar analgesia compared to the lidocaine/tetracaine patch during I&D of skin abscesses in the Emergency Department. Pain at presentation and following the procedure was similar in both groups.

Interventions

Sponsors

East Carolina University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE
Masking
QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Age\>18 years * Skin abscess in need of incision and drainage (judged by treating physician)

Exclusion criteria

* Allergy to lidocaine or tetracaine * Non-intact skin * Unable/unwilling to provide informed consent

Design outcomes

Primary

MeasureTime frameDescription
Change in VAS pain score over timeImmediately prior to starting I&D (Time 0); 2-5 minutes after start of I&D (Time 1); within 1 minute of completion of I&D (Time 2)VAS measured at each of the 3 time points noted above.

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026