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High Intensity Cycling Before SCUBA Diving Reduces Post-decompression Microparticle Production and Neutrophil Activation

High Intensity Cycling Before SCUBA Diving Reduces Post-decompression Microparticle Production and Neutrophil Activation

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT02064361
Enrollment
10
Registered
2014-02-17
Start date
2013-02-28
Completion date
2013-05-31
Last updated
2014-02-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Decompression Sickness, SCUBA Diving

Keywords

SCUBA diving, exercise,, microparticles, neutrophil activation,, high intensity exercise

Brief summary

The purpose of this study is to determine the impact of high intensity,anaerobic exercise, in the form of cycling, on SCUBA diving. Outcomes are determined by the quantification and subtype of circulating microparticles, complete blood counts, and the quantification of venous gas emboli, measured via transthoracic echocardiography, in the cardiac cavities.

Interventions

OTHERHigh intensity exercise

Subjects performed a repeated Wingate protocol for the exercise condition of the study. This consisted of 4, 30 s maximal efforts on a weight-braked cycle ergometer (Monark 894E, Monark Exercise AB, Sweden) with 4 min active recovery between efforts, preceded by a 5 min warm up. The resistance was set at 7.5% bodyweight for the intervals and 2% for the warm up and active recovery periods.

Sponsors

University of Maryland
CollaboratorOTHER
University of Split
Lead SponsorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
BASIC_SCIENCE
Masking
NONE

Eligibility

Sex/Gender
MALE
Age
18 Years to 65 Years
Healthy volunteers
Yes

Inclusion criteria

* Experienced divers (\> 250 logged dives) * Male * Physician clearance to dive

Exclusion criteria

* Prior incidence of decompression sickness

Design outcomes

Primary

MeasureTime frame
Change from baseline values of number of circulating microparticles per microliter of bloodPrior to exercise, prior to diving, 15 and 120 minutes after surfacing

Countries

Croatia, United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026